Neural mechanism for developing therapy for masseter muscle pain triggered by myofascial pain in the neck shoulder

开发治疗颈肩肌筋膜疼痛引发的咬肌疼痛的神经机制

• 批准号: 15K11272
• 负责人: KUBO Asako
• 金额: $ 3.08万
• 依托单位: Nihon University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K11272/
• 关键词: 咬筋痛; 顎関節症; 神経成長因子; 機械痛覚過敏; 三叉神経節; 延髄; 筋性疼痛; 中枢神経機構; 痛み; パッチクランプ法

项目成果

ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue.

• DOI: 10.1177/1744806916641680
• 发表时间: 2016
• 期刊: Molecular pain
• 影响因子: 3.3
• 作者: Nakaya Y;Tsuboi Y;Okada-Ogawa A;Shinoda M;Kubo A;Chen JY;Noma N;Batbold D;Imamura Y;Sessle BJ;Iwata K
• 通讯作者: Iwata K

Chondroitin sulfate suppresses the low-pH induced mechanical response in thin muscle afferents of rats

硫酸软骨素抑制低 pH 诱导的大鼠薄肌传入机械反应

• 发表时间: 2017
• 作者: Norio Hotta;Asako Kubo;Kazue Mizumura
• 通讯作者: Kazue Mizumura

Oxytocin suppresses facial mechanical hypersensitivity following nerve injury via voltage-gated potassium channel mechanisms in the rat trigeminal ganglia

催产素通过大鼠三叉神经节的电压门控钾通道机制抑制神经损伤后的面部机械过敏

• 发表时间: 2017
• 作者: Asako Kubo;Masamichi Shinoda;David C. Yeomans;Koichi Iwata
• 通讯作者: Koichi Iwata

Orofacial cutaneous mechanical hypersensitivity following infraorbital nerve injury is attenuated by peripheral Oxytocin in rats.

大鼠中外周催产素可减轻眶下神经损伤后的口面部皮肤机械过敏。

• 发表时间: 2016
• 作者: A Kubo;M Shinoda;D Yeomans;K Iwata
• 通讯作者: K Iwata

Oxytocin alleviates orofacial hypersensitivity following infraorbital nerve injury in rats.

催产素可减轻大鼠眶下神经损伤后的口面部过敏。

• 发表时间: 2015
• 作者: Asako KUBO;Masamichi SHINODA;David C. YEOMANS;Koichi IWATA
• 通讯作者: Koichi IWATA