Development of Portable Fiber-Optic Laser Doppler Velocimetry Sensor for Measurement of Local Flow Velocity of Blood and Opaque Multi-Phase Fluids

开发便携式光纤激光多普勒测速传感器，用于测量血液和不透明多相流体的局部流速

• 批准号: 09555067
• 负责人: OHBA Kenkichi
• 金额: $ 6.34万
• 依托单位: Kansai University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09555067/
• 关键词: Fiber optic sensor; Laser Doppler velocimetry sensor; Blood flow measurement; Opaque fluid flow measurement; Distributed index lens; Obliquely truncated conical head; Sensor head incorporated inside syringe needle; Insertion into blood vessel; 光ファ

In order to measure the local velocity field in opaque fluids like blood and/or multi-phase fluids, a new fiber-optic laser Doppler velocimetry sensor has been developed. In the course of the present research for the development the followings have been elucidated :After obtaining the characteristics of laser light extinction in bovine blood of several different dilution rates and in mixtures of white pigment and water, the flow velocity of diluted bovine blood contained in an annular open channel which is placed on a rotating disc has been measured by using the present fiber optic sensor. Its pickup consists of a distributed index lens of 2mm in diameter attached at the tip of two fibers being joined side by side in parallel. Although the sensor is capable of making a accurate measurement of local velocity of diluted blood up to 20%, it cannot measure the velocity of thicker blood, because the blood used is considered to has worse quality than intact blood in vivo.The sensor head has … More been improved ; Firstly, its tip is shaped to have an obliquely truncated cone in order to decrease a disturbance of flow by the head and also to diminish undesirable light scattered from the tip of the head. Secondly, a smaller DIL lens of 1mm in diameter is adopted instead of the 2mm- diameter DIL lens to make it inserted inside of the needle of a hypodermic syringe. Thirdly, a mono-fiber optical system is adopted instead of the dual-fiber optical system to increase the sensitivity for opaque fluid. Fourthly, a bonding agent of being hardened by ultraviolet light is used between the fiber and the DIL lens to diminish an undesirable scattered light. As a result, the maximum measurable concentration of the semi-opaque suspension fluid is increase to be four times greater than the original one.By inserting the improved sensor head incorporated inside the syringe needle into a modeled blood vessel of silicone rubber, a high concentration suspension fluid of white pigment as a model blood flowing in the tube has been measured. As a result, the velocity distribution of a paraboloid of revolution characterizing the developed steady laminar flow is accurately obtained. Hence, it can be concluded that the prospect of success is good to measure the local blood velocity in blood vessel in vivo by directly inserting the sensor head into the vessel. Less

为了测量血液和多相流体等不透明流体中的局部速度场，研制了一种新型光纤激光多普勒测速传感器。在本研究的过程中，阐明了以下几点：在获得了几种不同稀释率的牛血和白色素与水的混合物中的激光消光特性后，利用本光纤传感器测量了放置在旋转圆盘上的环形开放通道中稀释的牛血的流速。它的拾取器由直径为2 mm的分布折射率透镜组成，该透镜固定在两根平行连接的光纤的顶端。虽然该传感器能够准确测量稀释血液的局部速度高达20%，但它不能测量稠血的速度，因为所用血液的质量被认为在活体内比完整血液更差。传感器头上有…更多的改进；首先，它的尖端被塑造成有一个斜截锥，以减少头部的流动扰动，也减少从头部尖端散射的不希望看到的光线。其次，采用直径1 mm的较小的DIL透镜代替直径2 mm的DIL透镜，将其插入皮下注射器的针头内。第三，采用单光纤系统代替双光纤系统，提高了对不透明流体的灵敏度。第四，在光纤和DIL透镜之间使用紫外光硬化的粘结剂，以消除不希望的散射光。通过将改进后的传感器头插入硅橡胶模型血管中，测量了高浓度白色颜料悬浮液作为模型血液在管内流动的情况。结果准确地得到了表征发展的定常层流的旋转抛物面的速度分布。因此，通过将传感器头直接插入血管内，在活体血管内测量局部血流速度具有良好的成功前景。较少

项目成果

西山,正之・大場,謙吉: "光ファイバーLDVセンサーの開発(DILセンサーヘッドの小型化)" 日本機械学会講演論文集. No.97-72. 251-252 (1998)

Nishiyama, Masayuki 和 Ohba, Kenkichi：“光纤 LDV 传感器的开发（DIL 传感器头的小型化）”日本机械工程师学会会议记录第 97-72 号（1998 年）。

武重光彦、大場謙吉、西山正之: "血管内の局所血流速測定用光ファイバーLDVセンサーの開発"日本機械学会第10回バイオエンジニアリング学術講演会・秋季セミナー講演論文集. 99-36. 29-30 (1999)

Mitsuhiko Takeshige、Kenkichi Ohba、Masayuki Nishiyama：“用于测量血管局部血流速度的光纤 LDV 传感器的开发”日本机械工程学会第十届生物工程学术会议/秋季研讨会论文集 99-36。 (1999)

K. Ohba, M. Nishiyama and K. Korenaga: "Development of fiber-optic laser Doppler velocimeter sensor for Measurement of local blood velocity"Proceeding of 9ィイD1thィエD1 International Symposium on Applications of Laser Techniques to Fluid mechanics. 28. 3. 1-

K. Ohba、M. Nishiyama 和 K. Korenaga：“用于测量局部血流速度的光纤激光多普勒测速传感器的开发”9D1D1 激光技术在流体力学应用国际研讨会论文集 28 .3.1-。

K.Ohba,M.Nishiyama & K.Korenaga: "Development of fiber optic laser Doppler velocimeter sensor for measurement of local blood velocity" Proceedings of 9th International Symposium on Appl-ications of Laser Techniques to Fluid Mechanics. Vol.2. 28.3.1-28.3.5

大场 K、西山 M

池田和之、大場謙吉、板東潔: "光ファイバーLDVセンサーへッド周りの流れ場の数値シミュレーション"日本機械学会講演論文集. 984-1. 43-44 (1998)

Kazuyuki Ikeda、Kenkichi Ohba、Kiyoshi Bando：“光纤 LDV 传感器头周围流场的数值模拟”日本机械工程师学会会议记录 984-1（1998）。