Identification of pancreatic cancer specific metabolites by metabolome mapping and application possibility for diagnostic biomarker.

通过代谢组图谱鉴定胰腺癌特异性代谢物以及诊断生物标志物的应用可能性。

• 批准号: 26462066
• 负责人: TORATA Nobuhiro
• 金额: $ 3.16万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26462066/
• 关键词: MALDI-MSI; Energy Charge; 凍結組織アレイ; バイオマーカー探索

项目成果

Metabolic profiling-based data-mining for an effective chemical combination to induce apoptosis of cancer cells.

• DOI: 10.1038/srep09474
• 发表时间: 2015-03-31
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Kumazoe M;Fujimura Y;Hidaka S;Kim Y;Murayama K;Takai M;Huang Y;Yamashita S;Murata M;Miura D;Wariishi H;Maeda-Yamamoto M;Tachibana H
• 通讯作者: Tachibana H

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells.

• DOI: 10.18632/oncotarget.15430
• 发表时间: 2017-03-14
• 期刊: Oncotarget
• 作者: Okumura T;Ohuchida K;Sada M;Abe T;Endo S;Koikawa K;Iwamoto C;Miura D;Mizuuchi Y;Moriyama T;Nakata K;Miyasaka Y;Manabe T;Ohtsuka T;Nagai E;Mizumoto K;Oda Y;Hashizume M;Nakamura M
• 通讯作者: Nakamura M

Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells

• DOI: 10.1507/endocrj.ej16-0467
• 发表时间: 2017-01-01
• 期刊: ENDOCRINE JOURNAL
• 影响因子: 2
• 作者: Li, Bing;Baba, Takashi;Morohashi, Ken-ichirou
• 通讯作者: Morohashi, Ken-ichirou

Tissue tablet method: an efficient tissue banking procedure applicable to both molecular analysis and frozen tissue microarray

组织片法：一种适用于分子分析和冷冻组织微阵列的高效组织库程序

• DOI: 10.1016/j.humpath.2013.08.013
• 发表时间: 2014
• 期刊: Hum Pathol
• 影响因子: 3.3
• 作者: Torata N;Ohuchida K;Akagawa S;Cui L;Kozono S;Mizumoto K;Aishima S;Oda Y;Tanaka M
• 通讯作者: Tanaka M

MALDI mass spectrometry imaging profile of low molecular metabolites in breast carcinoma tissues embedded in frozen tissue microarray

冷冻组织微阵列中乳腺癌组织中低分子代谢物的 MALDI 质谱成像图谱

• 发表时间: 2015
• 作者: 北川裕久;寺川裕史;牧野勇;田島秀浩;宮下知治;太田哲生;八木康道;池田博子;大坪公士郎;蒲田敏文;Torata N,Kubo M,Miura D,Ohuchida K,Miyazaki T,Fujimura Y,Hayakawa E,Kai M,Oda Y,Mizumoto K,Hashizume M,Nakamura M
• 通讯作者: Torata N,Kubo M,Miura D,Ohuchida K,Miyazaki T,Fujimura Y,Hayakawa E,Kai M,Oda Y,Mizumoto K,Hashizume M,Nakamura M