Elucidation of the pathophysiology of acute heart failure and development of novel therapies based on clinical data and epigenetics

基于临床数据和表观遗传学阐明急性心力衰竭的病理生理学并开发新疗法

• 批准号: 26461086
• 负责人: MATSUSHITA Kenichi
• 金额: $ 3.08万
• 依托单位: Kyorin University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461086/
• 关键词: 循環器; 心不全

项目成果

Differences between patients with diastolic heart failure and those with systolic heart failure in the way that hypertension is involved in acute worsening renal function

舒张性心力衰竭和收缩性心力衰竭患者之间的差异在于高血压与肾功能急性恶化的关系

• 发表时间: 2015
• 作者: Yamagishi T;Matsushita K;Minamishima T;Goda A;Sakata K;Satoh T;Yoshino H.
• 通讯作者: Yoshino H.

Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications.

• DOI: 10.1155/2016/2892840
• 发表时间: 2016
• 期刊: Stem cells international
• 影响因子: 4.3
• 作者: Matsushita K

Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.

• DOI: 10.1038/labinvest.2016.66
• 发表时间: 2016-08
• 期刊: Laboratory investigation; a journal of technical methods and pathology
• 作者: Matsushita K;Wu Y;Pratt RE;Dzau VJ
• 通讯作者: Dzau VJ

急性心不全

急性心力衰竭

• 发表时间: 2014
• 期刊: 杏林医学会雑誌
• 作者: Matsushita K;Wu Y;Pratt RE;Dzau VJ.;松下健一
• 通讯作者: 松下健一

Nuclear hormone receptor LXRα inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling.

• DOI: 10.1038/labinvest.2015.141
• 发表时间: 2016-02
• 期刊: Laboratory investigation; a journal of technical methods and pathology
• 作者: Matsushita K;Morello F;Zhang Z;Masuda T;Iwanaga S;Steffensen KR;Gustafsson JÅ;Pratt RE;Dzau VJ
• 通讯作者: Dzau VJ