In vivo visualization of synuclein deposits in Parkinson's disease and its clinical applicability

帕金森病突触核蛋白沉积物的体内可视化及其临床应用

• 批准号: 26461303
• 负责人: Kikuchi Akio
• 金额: $ 3.08万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26461303/
• 关键词: パーキンソン病; PET; [11C] BF-227; α-シヌクレイン; [11C]BF-227

项目成果

Variants associated with Gaucher disease in multiple system atrophy.

• DOI: 10.1002/acn3.185
• 发表时间: 2015-04
• 期刊: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
• 影响因子: 5.3
• 作者: Mitsui, Jun;Matsukawa, Takashi;Sasaki, Hidenao;Yabe, Ichiro;Matsushima, Masaaki;Duerr, Alexandra;Brice, Alexis;Takashima, Hiroshi;Kikuchi, Akio;Aoki, Masashi;Ishiura, Hiroyuki;Yasuda, Tsutomu;Date, Hidetoshi;Ahsan, Budrul;Iwata, Atsushi;Goto, Jun;Ichikawa, Yaeko;Nakahara, Yasuo;Momose, Yoshio;Takahashi, Yuji;Hara, Kenju;Kakita, Akiyoshi;Yamada, Mitsunori;Takahashi, Hitoshi;Onodera, Osamu;Nishizawa, Masatoyo;Watanabe, Hirohisa;Ito, Mizuki;Sobue, Gen;Ishikawa, Kinya;Mizusawa, Hidehiro;Kanai, Kazuaki;Hattori, Takamichi;Kuwabara, Satoshi;Arai, Kimihito;Koyano, Shigeru;Kuroiwa, Yoshiyuki;Hasegawa, Kazuko;Yuasa, Tatsuhiko;Yasui, Kenichi;Nakashima, Kenji;Ito, Hijiri;Izumi, Yuishin;Kaji, Ryuji;Kato, Takeo;Kusunoki, Susumu;Osaki, Yasushi;Horiuchi, Masahiro;Kondo, Tomoyoshi;Murayama, Shigeo;Hattori, Nobutaka;Yamamoto, Mitsutoshi;Murata, Miho;Satake, Wataru;Toda, Tatsushi;Filla, Alessandro;Klockgether, Thomas;Wuellner, Ullrich;Nicholson, Garth;Gilman, Sid;Tanner, Caroline M.;Kukull, Walter A.;Stern, Mathew B.;Lee, Virginia M. -Y.;Trojanowski, John Q.;Masliah, Eliezer;Low, Phillip A.;Sandroni, Paola;Ozelius, Laurie J.;Foroud, Tatiana;Tsuji, Shoji
• 通讯作者: Tsuji, Shoji

[11C]BF-227 PETにおける多系統萎縮症脳内α-シヌクレインの経時的変化

[11C]BF-227 PET 中多系统萎缩脑中 α-突触核蛋白的时程

• 发表时间: 2015
• 作者: 菊池昭夫;岡村信行;馬場 徹;長谷川隆文;菅野直人;今野昌俊;三浦永美子;大嶋龍司;吉田隼;古本祥三;平岡宏太良;谷内一彦;田代 学;工藤幸司;糸山泰人;武田 篤;青木正志.
• 通讯作者: 青木正志.

Subgroup differences in “brain-type” transferrin and alpha-synuclein in Parkinson's disease and multiple system atrophy

帕金森病和多系统萎缩中“脑型”转铁蛋白和α-突触核蛋白的亚组差异

• DOI: 10.1093/jb/mvw015
• 发表时间: 2016
• 期刊: The Journal of Biochemistry
• 作者: A Yoshihara;M Fukatsu;K Hoshi;Y Hashimoto;et. al
• 通讯作者: et. al

Longitudinal [11C]BF-227 PET study in MSA-C patients

MSA-C 患者的纵向 [11C]BF-227 PET 研究

• 发表时间: 2015
• 作者: Kikuchi A;Okamura N;Tashiro M;Furumoto S;Hasegawa T;Watanuki S;Hiraoka K;Funaki Y;Kobayashi M;Sugeno N;Baba T;Konno M;Miura E;Oshima R;Yoshida S;Iwata R;Takahashi S;Fukuda H;Itoyama Y;Arai H;Kudo Y;Yanai K;Aoki M;Takeda A.
• 通讯作者: Takeda A.

Pathogenesis of multiple system atrophy.

多系统萎缩的发病机制。

• DOI: 10.1007/s00415-014-7271-5
• 发表时间: 2013
• 期刊: Neurology and Clinical Neuroscience
• 影响因子: 0.4
• 作者: Hasegawa T;Kikuchi A;Takeda A.
• 通讯作者: Takeda A.