课题基金 / 基金详情

SYNTHESIS OF RADIOSENSITIZING AGENTS

SYNTHESIS OF RADIOSENSITIZING AGENTS
放射增敏剂的合成
批准号：
3614814
负责人：
MARTIN TRACEY
金额：
$49.71万
依托单位：
SRI INTERNATIONAL
依托单位国家：
美国
项目类别：
财政年份：
1987
资助国家：
美国
项目状态：
已结题
起止时间：
1987-06-01 至 1990-05-31
来源：
https://reporter.nih.gov/project-details/3614814
关键词：
cytotoxicity drug design /synthesis /production hamsters human tissue nitrogenous heterocyclic compound radiation dosage radiosensitizer tissue /cell culture

项目摘要

项目成果

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中文摘要
翻译
本合同的目的是设计、综合和表征
英文摘要
The objectives of this contract are to design, synthesize and characterize new and/or novel non-nitro radiosensitizers. The contractor is expected to develop the leads which result from the screening effort (NCI contract N01-CM-67868), which evaluates compounds for their radiosensitivity activity. The contractor is expected to synthesize analogs of the lead compounds and develop in vitro and in vivo data on the efficacy of these compounds as radiosensitizers. New radiosensitizers for clinical use are expected from this contract.
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