The development of novel antibiotics for drug resistant infections

针对耐药感染的新型抗生素的开发

• 批准号: 10024609
• 金额: $ 8.67万
• 依托单位: OXFORD DRUG DESIGN LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10024609
• 关键词: development; novel; antibiotics; drug; resistant

The emergence of resistance to antibiotics is a major health concern. To address this concern, this project will address multiple aspects of antibacterial resistance, bringing together complementary expertise in the UK and China. Antibiotics are widely used in agriculture, where they have a valid role in protecting farm animals from disease and increasing food production. However, the use of antibiotics that are also used to treat humans could lead to increased antimicrobial resistance. The aim of this project is to develop classes of antibiotic that are specific to a species of bacterium that cause infections in pigs. This which would enable reduced use of human antibiotics in farming and mean that animal welfare can be protected without the risk of further increasing antibiotic resistance to antibiotics important for the treatment of human infections .

抗生素耐药性的出现是一个主要的健康问题。为了解决这一问题，该项目将汇集英国和中国的互补专业知识，解决抗菌素耐药性的多个方面。抗生素广泛应用于农业，在保护农场动物免受疾病和增加粮食产量方面发挥着有效作用。然而，使用也用于治疗人类的抗生素可能会导致抗菌素耐药性增加。该项目的目的是开发针对引起猪感染的细菌种类的抗生素。这将能够减少农业中人类抗生素的使用，并意味着动物福利可以得到保护，而不会出现进一步增加对治疗人类感染重要的抗生素的抗生素耐药性的风险。