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Project Summary The project outlines our plans to develop a rapid, point-of-care diagnostic test for the novel SARS-CoV-2 virus that can be used in resource-limited locations. The foundation of the project is a highly selective chemiluminescent reporter probe that produces light when activated by the major viral protease SARS-CoV-2 Mpro. This approach will enable rapid testing (<30 min) of easily obtained clinical samples (i.e., saliva) using a detector that has limited power needs and that can interface with standard smart phones to provide a diagnosis.
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Covalent inhibitors of host cell entry by SARS-CoV-2 for treatment of COVID-19
  • 批准号:
    10377746
  • 项目类别:
  • 资助金额:
    $19.68万
  • 财政年份:
    2022
  • 负责人:
    Matthew Bogyo
  • 依托单位:
Covalent inhibitors of host cell entry by SARS-CoV-2 for treatment of COVID-19
  • 批准号:
    10611435
  • 项目类别:
  • 资助金额:
    $23.61万
  • 财政年份:
    2022
  • 负责人:
    Matthew Bogyo
  • 依托单位:
Targeting bacterial proteases involved in PAR signaling to treat inflammatory bowel diseases
  • 批准号:
    10389858
  • 项目类别:
  • 资助金额:
    $50.97万
  • 财政年份:
    2021
  • 负责人:
    Matthew Bogyo
  • 依托单位:
Targeting bacterial proteases involved in PAR signaling to treat inflammatory bowel diseases
  • 批准号:
    10670358
  • 项目类别:
  • 资助金额:
    $45.8万
  • 财政年份:
    2021
  • 负责人:
    Matthew Bogyo
  • 依托单位:
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