Clinical and Population Sciences Core

临床和人口科学核心

• 批准号: 10160760
• 负责人: Manya Magnus
• 金额: $ 15.78万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10160760
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Address; Administrative Supplement; Applications Grants; Award; Biological; Biometry; Caring; Clinic; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Communities; Consultations; Data; Data Analyses; Database Management Systems; Development; Discipline; District of Columbia; Ensure; Epidemic; Epidemiology; Ethics; Funding; Government; Grant; Grant Review; HIV; Hospitals; Institution; Leadership; Left; Manuscripts; Mission; Patients; Persons; Population; Population Sciences; Population Study; Positioning Attribute; Prevention; Procedures; Protocols documentation; Public Health; Publications; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Risk; Sample Size; Science; Scientist; Series; Services; Specimen; Statistical Data Interpretation; Training; United States National Institutes of Health; Washington; biobank; cohort; epidemiology study; experience; genetic linkage analysis; improved; innovation; member; novel strategies; pre-exposure prophylaxis; programs; recruit; service providers

CLINICAL AND POPULATION SCIENCES CORE (CORE D) PROJECT SUMMARY The Clinical and Population Sciences (CPS) Core is an essential resource for DC CFAR investigators, providing clinical, biostatistics and epidemiology services to support HIV research in a wide range of disciplines and across multiple institutions. The CPS Core is led by an experienced team of senior HIV investigators: Dr. Princy Kumar (GU, Director - Clinical), Dr. Sam Simmens (GW, Co-Director - Biostatistics) and Dr. Manya Magnus (GW, Co-Director - Epidemiology). The Specific Aims of the Core are: 1) to provide comprehensive clinical, biostatistics and epidemiology consultation services to DC CFAR investigators; and 2) to expand the magnitude and impact of clinical and population HIV science in Washington, DC. Since 2015, the Core leadership and CPS Core service providers have provided >360 Core services. The most frequently requested services were consultations on study design and biostatistics, reviews of grant proposals and manuscripts, data analysis, and guidance on study implementation issues such as recruitment and retention. The Core has connected investigators with scientific collaborators and community members and facilitated access to existing cohort data and biorepositories. From 2015-2019, these services supported 56 unique investigators, 58 publications, 66 pilot award applications, seven administrative supplements, 59 NIH grant submissions and 10 new NIH grants. Innovative programs such as the No Investigator Left Behind and MACC Scholars initiatives and enhanced access to cohorts and specimens though the MACS/WIHS Combined Cohort Study, DC Cohort and HPTN CRS contribute to the Core's capacity to achieve its aims and support the overall mission of the DC CFAR.

临床和人口科学核心（核心D） 项目摘要 临床和人口科学（CPS）核心是DC CFAR研究人员的重要资源， 提供临床、生物统计学和流行病学服务，以支持多个学科的艾滋病毒研究 和多个机构。CPS核心是由一个经验丰富的高级艾滋病毒研究人员团队领导： Dr. Samy Kumar（GU，临床总监）、Dr. Sam Simmens（GW，生物统计学联席总监）和Dr. Manya Magnus（GW，流行病学联合主任）。核心的具体目标是：1）提供全面的 为DC CFAR调查人员提供临床、生物统计学和流行病学咨询服务;以及2）扩大 在华盛顿，DC的临床和人群HIV科学的规模和影响。 自2015年以来，Core领导层和CPS Core服务提供商提供了超过360项Core服务。最 经常要求提供的服务是关于研究设计和生物统计学的咨询， 和手稿，数据分析和指导研究实施问题，如招募和 潴留核心将研究人员与科学合作者和社区成员联系起来， 促进了对现有队列数据和生物储存库的访问。从2015年到2019年，这些服务支持了56个 独特的研究者，58篇出版物，66项试点奖励申请，7份行政补充材料，59份NIH 10个新的NIH赠款。创新项目，如“不让一个调查员掉队”， 通过MACS/WIHS组合，MACC学者倡议并增强了对队列和标本的访问 队列研究、DC队列和HPTN CRS有助于核心实现其目标并支持 DC CFAR的总体使命。