Clinical and Population Sciences Core

临床和人口科学核心(核心D) 项目总结 临床和人口科学(CPS)核心是DC CFAR调查人员的重要资源， 提供临床、生物统计和流行病学服务，以支持广泛学科的艾滋病毒研究 以及跨多个机构。CPS核心由一支经验丰富的高级艾滋病毒调查团队领导：Dr。 Kumar公主(GU，临床主任)、Sam Simmens博士(GW，生物统计学联席主任)和Manya博士 Magnus(GW，流行病学联席主任)。核心的具体目标是：1)提供全面的 向华盛顿CFAR调查人员提供临床、生物统计和流行病学咨询服务；以及2)扩大 华盛顿特区临床和人口艾滋病毒科学的规模和影响。 自2015年以来，核心领导力和CPS核心服务提供商提供了&gt；360核心服务。最多的 经常被要求的服务是关于研究设计和生物统计的咨询、对赠款提案的审查 和手稿，数据分析和关于研究执行问题的指导，如征聘和 留存。核心将调查人员与科学合作者和社区成员联系起来，并 便利了对现有队列数据和生物储存库的访问。从2015-2019年，这些服务支持了56 独一无二的调查人员、58份出版物、66份试点奖项申请、7份行政副刊、59份NIH 提交的拨款和10笔新的NIH拨款。创新节目，如《不落下任何调查者》和 MACC学者倡议和通过MACS/WIHS合并更多地获得队列和标本 队列研究、DC队列和HPTN CRS有助于提高核心实现其目标的能力，并支持 哥伦比亚特区CFAR的总体任务。

CLINICAL AND POPULATION SCIENCES CORE (CORE D) PROJECT SUMMARY The Clinical and Population Sciences (CPS) Core is an essential resource for DC CFAR investigators, providing clinical, biostatistics and epidemiology services to support HIV research in a wide range of disciplines and across multiple institutions. The CPS Core is led by an experienced team of senior HIV investigators: Dr. Princy Kumar (GU, Director - Clinical), Dr. Sam Simmens (GW, Co-Director - Biostatistics) and Dr. Manya Magnus (GW, Co-Director - Epidemiology). The Specific Aims of the Core are: 1) to provide comprehensive clinical, biostatistics and epidemiology consultation services to DC CFAR investigators; and 2) to expand the magnitude and impact of clinical and population HIV science in Washington, DC. Since 2015, the Core leadership and CPS Core service providers have provided >360 Core services. The most frequently requested services were consultations on study design and biostatistics, reviews of grant proposals and manuscripts, data analysis, and guidance on study implementation issues such as recruitment and retention. The Core has connected investigators with scientific collaborators and community members and facilitated access to existing cohort data and biorepositories. From 2015-2019, these services supported 56 unique investigators, 58 publications, 66 pilot award applications, seven administrative supplements, 59 NIH grant submissions and 10 new NIH grants. Innovative programs such as the No Investigator Left Behind and MACC Scholars initiatives and enhanced access to cohorts and specimens though the MACS/WIHS Combined Cohort Study, DC Cohort and HPTN CRS contribute to the Core's capacity to achieve its aims and support the overall mission of the DC CFAR.