Biostatistics Core

生物统计学核心

• 批准号: 10160832
• 负责人: Mark R Conaway
• 金额: $ 5.8万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10160832
• 关键词: Address; Animal Model; Area; Biometry; Biostatistics Core; Cell Line; Clinical; Data; Data Analyses; Ensure; Experimental Designs; Goals; Health Sciences; Human Resources; Knowledge; Laboratories; Manuscripts; Metabolism; Methodology; Methods; Modeling; Patient-Focused Outcomes; Patients; Preparation; Public Health; Research; Research Design; Research Personnel; Resources; Sample Size; Sampling Studies; Services; Source; Specific qualifier value; Sphingolipids; Technology; Testing; Time; Universities; Variant; Virginia; archive data; archived data; data management; data repository; data sharing; design; experience; experimental study; human subject; improved; insight; medical schools; multiple data sources; novel; preservation; programs; success; synergism; tool

PROJECT SUMMARY The Biostatistics Core will provide the timely and high-quality statistical support necessary for the success of the Program Project. The Biostatistical support will center on three specific aims: 1) provide support for the design, analysis and proper inference from the laboratory and patient sample studies conducted in the Projects, 2) apply state-of-the-art statistical tools to gain additional insights into data created in the Projects and 3) provide support for combining data from multiple sources. The general analysis principles include methods to validate assumptions; improve precision by removing known sources of variation, such as experiment to experiment variability; control for multiple hypothesis testing; and validate models. The data and programming support will provide expertise in merging data from multiple sources and archiving data to allow the results of data analyses to be preserved and reproduced. Biostatistics support is critical for the success of the Program Project. The Biostatistics Core provides easy and guaranteed access for investigators and also allows the biostatisticians to specialize in the Project areas regarding content knowledge and appropriate statistical methodology. A dedicated Core provides timely and high-quality biostatistical services as its focus.

项目总结 生物统计核心将提供及时和高质量的统计支持，以取得成功 计划项目。生物统计支持将集中在三个具体目标上：1)为 从实验室和患者样本研究中进行的设计、分析和适当的推断 项目，2)应用最先进的统计工具，以获得对项目中创建的数据的更多见解 以及3)提供对来自多个源的数据组合的支持。一般分析原则包括 验证假设的方法；通过删除已知的变化源来提高精度，例如 实验以实验可变性；控制多重假设检验；并验证模型。数据和 编程支持将提供合并来自多个来源的数据和归档数据的专业知识，以便 数据分析的结果将被保存和复制。生物统计支持是成功的关键 计划项目。生物统计核心为研究人员提供了方便和有保障的访问途径，还 允许生物统计学家专门研究项目领域的内容知识和适当的 统计方法。一个专注的核心提供及时和高质量的生物统计服务作为其重点。