Visual Sciences Training Program

视觉科学培训计划

• 批准号: 10171853
• 负责人: Johannes Friedrich von Lintig
• 金额: $ 17.45万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10171853
• 关键词: Training Programs; vision science

Twenty-five faculty affiliated with the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU) seek renewed support for the Visual Sciences Training Program (VSTP). The faculty comprises a multi-disciplinary vision sciences research community of basic and clinical scientists encompassing the Departments of, Epidemiology and Biostatistics, Medicine, Molecular Biology & Microbiology, , Ophthalmology & Visual Sciences (UH), Ophthalmology (CCLCM), Pathology, Pharmacology, Physiology & Biophysics, and Systems Biology & Bioinformatics. This group’s capabilities and productivity in the field of vision research has led to its support as a priority focus in strategic planning at Case Western Reserve University. The momentum associated with the recent expansion of the NEI Core grant-supported Visual Sciences Research Center and the awards of two R24 and U01 grants from the NEI have bolstered a critical mass of vision scientists with extramural support for their research. This atmosphere affords an ideal training opportunity for vision scientists. The Visual Sciences Research Center and collaborative research of its participating faculty provide an overall framework for the Visual Sciences Training Program. In addition, as vision research has expanded at CWRU, there has been a natural evolution of research/training groups that have distinct identities but also considerable overlap. This T32 Institutional Training Grant renewal application is organized according to four major vision science research themes: (a) Retinal Development and Function; (b) Retinal Disorders: Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD); (c) Biochemistry, Cell Biology, Immunology of Eye Diseases; and (d) Genetics, Physiology, and Epidemiology of Eye Diseases. These themes, involving groups of collaborating faculty, students and postdoctoral fellows, provide a natural way to organize the training program. In addition, there is a strong translational theme focused on therapeutic discovery that is an important aspect of all four research clusters. Continued support is requested for five pre-doctoral student positions and one post-doctoral position in all years. The rich research environment for vision science serves to attract trainees of the highest potential. Students receive training in Ph.D. program-specific, vision research theme-specific, and laboratory-based settings. Collectively, this approach ensures that our trainees are equipped with the broad interdisciplinary knowledge and technical skills needed to pursue biologically and clinically relevant research questions. The training program is supported by the resources of the faculty with vision science research expertise and their collaborators, by the Core Modules of the Visual Science Research Center, and by the broader resources of Case Western Reserve University, University Hospitals of Cleveland, the Cleveland Clinic Lerner Research and Cole Eye Institutes, and the Louis Stokes Cleveland VA Medical Research Center.

25名教师隶属于凯斯西储的视觉科学研究中心（VSRC） 大学（CWRU）寻求视觉科学培训计划（VSTP）的新支持。学院 由基础和临床科学家组成的多学科视觉科学研究社区 包括部门，流行病学和生物统计学，医学，分子生物学和 微生物学，眼科学和视觉科学（UH），眼科学（CCLCM），病理学，药理学， 生理学与生物物理学，系统生物学与生物信息学。该小组的能力和生产力， 视觉领域的研究已经成为凯斯西控战略规划的重点 储备大学。与最近扩大NEI核心补助金支持的势头相关 视觉科学研究中心以及NEI的两项R24和U 01赠款的授予， 视觉科学家的临界质量与校外支持他们的研究。这种气氛提供了一个理想的 视觉科学家的培训机会。视觉科学研究中心和 它的参与教师提供了视觉科学培训计划的整体框架。另外作为 视觉研究在CWRU已经扩大，研究/培训小组已经自然演变， 有着不同的身份，但也有相当多的重叠。T32机构培训补助金更新申请 根据四个主要的视觉科学研究主题组织：（a）视网膜发育和功能; (b)视网膜疾病：糖尿病视网膜病变（DR）和视网膜相关性黄斑变性（AMD）;（c） 生物化学、细胞生物学、免疫学及眼科疾病;及（d）遗传学、生理学及流行病学 眼部疾病。这些主题，涉及合作的教师，学生和博士后研究员群体， 提供一种自然的方式来组织培训计划。此外，还有一个强烈的翻译主题 专注于治疗发现，这是所有四个研究集群的重要方面。持续支持是 要求在所有年份提供五个博士前学生职位和一个博士后职位。丰富的研究 视觉科学的环境有助于吸引最具潜力的学员。学生接受培训， 博士项目特定、视觉研究主题特定和基于实验室的设置。总的来说，这 这种方法确保我们的学员具备广泛的跨学科知识和技术技能 需要追求生物学和临床相关的研究问题。该培训计划得到以下方面的支持： 具有视觉科学研究专业知识的教师及其合作者的资源，由核心模块 视觉科学研究中心，并通过凯斯西储大学更广泛的资源， 克利夫兰大学医院，克利夫兰诊所勒纳研究和科尔眼科研究所，以及路易斯 Stokes Cleveland VA医学研究中心