Technology-Dev-Core

技术开发（Tech Dev）核心 艾滋病毒/艾滋病护理点技术创新中心的技术开发核心， 西北大学（C-THAN）将支持专门设计的重要POC技术的开发， 为中低收入国家艾滋病毒感染者提供患者管理，重点是 撒哈拉以南非洲的诊断需求。我们将支持专门为低成本设计的技术项目， 医疗基础设施水平低或有限的资源环境，如电力、制冷设施有限 和/或中央供水系统。一个成功的测试将是用户友好的，只需要在其操作的本地培训 和维护，可低成本制造，低成本消耗品，快速结果，耐用，包含内部 设备/检测性能检查、自校准和错误诊断。C-THAN支持的项目将 符合HIV/AIDS研究的高优先级主题，能够适应低资源条件 环境，并在发展中国家商业化的可能性很高。C的一个独特之处- THAN是我们通过提供专项资金，促进中低收入国家本地技术发展的承诺 通过协调一致的努力，为专门针对艾滋病毒的POC技术提供本土解决方案的机会 照顾LMIC。这一目标得到了我们进入新兴非洲生物医学工程网络的支持 通过我们在尼日利亚和南非的合作伙伴，我们将建立一个强大的POC技术管道 通过确定诊断需求，招募满足这些需求的项目，监测资助项目的进展情况， 项目，提供服务和指导，以指导项目走向成熟，并促进项目的转让 用于临床评价。产出将是一系列具有高度临床影响的产品，这些产品是从一个良好的- 平衡的研究组合源于技术开发核心。

Summary Technology Development (Tech Dev) Core The Technology Development Core of the Center for Innovation in Point-of-Care Technologies for HIV/AIDS at Northwestern University (C-THAN) will support the development of vital POC technology specifically designed for patient management of people living with HIV in low and middle income countries with emphasis on the diagnostic needs in sub-Saharan Africa. We will support technology projects specifically designed for low resource settings with low or limited medical infrastructure such as restricted access to electricity, refrigeration and/or central water supply. A successful test will be user friendly, requiring only local training in its operation and maintenance, manufacturable at low cost with low cost consumables, rapid result, durable, contain internal checks of device/assay performance, self-calibration and error diagnosis. Projects supported by C-THAN will conform to high priority topics of HIV/AIDS research, be amenable to the conditions of low resource environments, and have high likelihood of commercialization in developing countries. A unique feature of C- THAN is our commitment to fostering local technology development in LMICs by providing specific funding opportunities for home-grown solutions via coordinated efforts to specifically incubate POC technology for HIV care in LMICs. This goal is supported by our access to a network of emerging African biomedical engineering programs through our partners in Nigeria and South Africa. We will build a robust pipeline of POC technology by identifying diagnostic needs, recruiting projects that meet those needs, monitoring progress made in funded projects, providing services and mentorship to guide projects to maturity, and facilitating the transfer of projects for clinical evaluation. The output will be a pipeline of products of high clinical impact developed from a well- balanced research portfolio originating from the Technology Development Core.