Neurology Physician Research Training Grant

内科科学家在将基础科学发现转化为新的临床研究成果方面占据着关键的地位。 治疗。在神经学领域，内科科学家一直走在许多领域的前列。 例如，在开发人类疾病的新模型、开发帕金森氏症的新临床治疗方法方面 疾病、癫痫和中风，并识别脑肿瘤、神经胶质前体细胞和 神经干细胞可能会促进新的疗法。然而，医生的相对数量和绝对数量 在过去的25年里，尽管美国国立卫生研究院的研究预算翻了一番，但科学家的人数一直在下降。 这个时代的一部分。这在很大程度上是因为对内科科学家的培训具有长期性。 美国国立卫生研究院在发布这一RFA研究教育计划时已经认识到了这个问题 神经病学、神经外科、神经病理学、神经放射学和急诊住院医师和研究员 医学。在这项拨款提案中，神经学研究教育项目的目标是培训神经学。 通过口头和书面直接研究性学习进行基础或临床科学研究的住院医生 科学的陈述和密集的导师职业发展。培训计划的结构 结合了几个层次的指导，并将时间集中在口头和书面演示上，最终达到了 在制作职业发展奖助金。这一培训计划得到了一位优秀的 加州大学洛杉矶分校神经科神经科学研究和教育的环境。该部门 一直是美国国立卫生研究院资助的十大神经科之一，并拥有大量的临床和基础研究 拥有多样化和资金充足的课程的教师。实习计划相对较大(每年9个)， 灵活地将选定的住院医生安排在研究计划中，并有培训许多人的记录 学术神经学家。拟议的教育计划利用了大量的神经科学。 神经科和相关部门内的社区有一个大型的和科学的 具有深入研究和过去培训经验的多元化导师群体。通过服务于整合 临床和基础神经学家与神经科住院医师在临床培训的背景下 计划，这笔赠款开发了一项翻译神经科学培训赠款。

Physician-scientists occupy a critical niche in the translation of basic science findings into new clinical treatments. Within the field of neurology, physician-scientists have been at the forefront, among many examples, in developing new models of human disease, developing new clinical treatments for Parkinson’s disease, epilepsy and stroke and identifying novel genetic signatures of brain tumors, glial progenitors and neural stem cells that may facilitate new therapies. However, the relative and absolute numbers of physician scientists have been declining over the past 25 years, despite the doubling of the NIH research budget during a portion of this epoch. This is in large part due to the prolonged nature of the training for a physician-scientist. The NIH has recognized this problem in the release of this RFA for Research Education Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine. The goal of the neurology research education program in this grant proposal is to train neurology residents in either basic or clinical science research through direct investigative study, oral and written scientific presentation and intensive mentored career development. The structure of the training program incorporates several tiers of mentoring and focused time on oral and written presentations, with a culmination in the production of career development grant. This training program is supported by an excellent environment for neuroscience research and education in the UCLA Neurology Department. The department has been a top ten NIH funded neurology department, and has a large clinical and basic research faculty with diverse and well-funded programs. The residency program is relatively large (9 per year) with flexibility to place selected residents in a research program, and has a track record of training many academic neurologists. The proposed education program takes advantage of the substantial neuroscience community within the Neurology Department and allied departments to have a large and scientifically diverse group of mentors with great depth of research and past training experience. By serving to integrate clinical and basic neuroscientists with Neurology residents in the context of their clinical training program, this grant develops a Translational Neuroscience Training Grant.