Repository Services for epidemiology studies

流行病学研究存储库服务

• 批准号: 10199836
• 负责人: Ethan Dmitrovsky
• 金额: $ 29.16万
• 依托单位: LEIDOS BIOMEDICAL RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-31 至 2020-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10199836
• 关键词: Acute Myelocytic Leukemia; Adenocarcinoma; Aplastic Anemia; Area; Biological; Burkitt Lymphoma; COVID-19; Chronic Lymphocytic Leukemia; Collection; Colorectal Cancer; Endometrial Carcinoma; Epidemiology; Equipment; Equipment and supply inventories; Ewings sarcoma; Fanconi' s Anemia; Helicobacter pylori; Hodgkin Disease; Human; Li-Fraumeni Syndrome; Maintenance; Malignant neoplasm of esophagus; Malignant neoplasm of lung; Malignant neoplasm of ovary; Malignant neoplasm of pancreas; Malignant neoplasm of pituitary gland; Malignant neoplasm of prostate; Malignant neoplasm of thyroid; Molecular Epidemiology; Myelofibrosis; Myotonic Dystrophy; Neurofibromatosis 1; Non-Hodgkin' s Lymphoma; Procedures; Program Development; Renal carcinoma; Rhabdomyosarcoma; Sampling; Services; Specimen; Transportation; Waldenstrom Macroglobulinemia; cold temperature; computerized; epidemiology study; malignant breast neoplasm; melanoma; osteosarcoma; preservation; repository

Under this project, a state-of-the-art repository for the storage of biospecimens for human epidemiology is operated. The repository activities include: sample receipt and distribution; ambient and low temperature storage of environmental and biological specimens; computerized sample inventory maintenance; maintain QC and QA programs; development or identification of biospecimen collection and storage conditions to preserve specimen and target analyte integrity; support to field centers in collection procedures, equipment, materials, and sample transportation, as requested. Support for Human molecular epidemiology research is focused in the following areas: Acute Myeloid Leukemia • Adenocarcinoma • Aplastic Anemia • Breast Cancer • Burkitt's Lymphoma • Chronic Lymphocytic Leukemia • Colorectal Cancer • COVID-19 • Endometrial Cancer • Esophageal Cancer • Ewing Sarcoma • Fanconi Anemia • Helicobacter pylori (H. pylori) • Hodgkin Lymphoma • Kidney Cancer • Li-Fraumeni Syndrome • Lung Cancer • Melanoma • Myelofibrosis • Myotonic Dystrophy • Neurofibromatosis 1 • Non-Hodgkin Lymphoma • Osteosarcoma • Ovarian Cancer • Pancreatic Cancer • Pituitary Cancer • Prostate Cancer • Rhabdomyosarcoma • Thyroid Cancer • Waldenstrom Macroglobulinemia

在这个项目下，一个最先进的人类流行病学生物标本储存库正在运作。存储库活动包括：样品接收和分发;环境和生物样本的室温和低温储存;计算机化样本库存维护;维护QC和QA程序;开发或确定生物样本采集和储存条件，以保持样本和目标分析物的完整性;根据要求，在采集程序、设备、材料和样本运输方面为现场中心提供支持。对人类分子流行病学研究的支持集中在以下领域：急性髓系白血病·腺癌·再生障碍性贫血·乳腺癌·伯基特淋巴瘤·慢性淋巴细胞白血病·结直肠癌· COVID-19 ·子宫内膜癌·食管癌·尤因肉瘤·范可尼贫血·幽门螺杆菌（H. pylori）·霍奇金淋巴瘤·肾癌· Li-Fraumeni综合征·肺癌·黑色素瘤·骨髓纤维化·肌强直性营养不良症·神经纤维瘤病1 ·非霍奇金淋巴瘤·骨肉瘤·卵巢癌·胰腺癌·胰腺癌·前列腺癌·横纹肌肉瘤·甲状腺癌·瓦尔登斯特伦巨球蛋白血症