IMMUNOLOGY QUALITY ASSESSMENT PROGRAM

免疫学质量评估计划

• 批准号: 10189437
• 负责人: Thomas Denny
• 金额: $ 150.75万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-30 至 2021-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10189437
• 关键词: CD8-Positive T-Lymphocytes; CD8B1 gene; Clinical Trials Network; Data; Data Management Resources; Diagnosis; Disease; Ensure; Freezing; Future; Immunologic Tests; Immunology; Laboratories; Laboratory Procedures; Libraries; Lymphocyte Count; Measures; Monitor; National Institute of Allergy and Infectious Disease; Online Systems; Performance; Peripheral Blood Mononuclear Cell; Procedures; Records; Reporting; Resolution; Resources; Site; Specific qualifier value; Testing; Training; base; computerized; cost; instrument; new technology; novel; programs; repository; technology validation

The purpose of the Immunology Quality Assessment Program (IQA) is to continue and provide a resource to (1) evaluate the abilities of U.S. and non-U.S. laboratories to accurately and reliably perform study-specified immunological tests (with focus on CD4 and CD8 T cell lymphocyte counts and percentages) and viable PBMC freezing, (2) advise and train when deficiencies are identified, (3) evaluate immunology-based novel technologies (with focus on novel, simple tests for diagnosis and disease monitoring) for implementation in multi-site NIAID trials, and (4) maintain a computerized data management system and document library that include lab performance data and guidance documents. IQA will continue to support laboratories that are part of current and future NIAID-sponsored clinical trial networks

免疫学质量评估计划 (IQA) 的目的是继续并提供资源，以 (1) 评估美国和非美国实验室准确可靠地执行研究特定免疫学测试（重点关注 CD4 和 CD8 T 细胞淋巴细胞计数和百分比）和可行 PBMC 冷冻的能力，(2) 在发现缺陷时提供建议和培训，(3) 评估 基于免疫学的新技术（重点是新颖、简单的诊断和疾病监测测试），用于在多站点 NIAID 试验中实施，以及 (4) 维护计算机化数据管理系统和文档库，其中包括实验室性能数据和指导文件。 IQA 将继续支持属于当前和未来 NIAID 赞助的临床试验网络一部分的实验室