Digital Technology Core

项目总结：数字技术核心 考虑到传统临床评估在精确绘制变化轨迹方面的局限性，我们的研究 社区越来越多地寻求将连续的、真实的和客观的方法结合起来 使用无处不在的 ORCATECH(俄勒冈州老龄化与技术中心)的计算平台和方法。这是一项新的 方法在痴呆症研究的许多领域都有重要的应用，而不仅仅是早期检测，例如 照顾者/照顾者活动；机构环境中的骚动；以及目标数字生物标记物 睡眠、体力活动和环境。这些技术的使用不仅限于评估，还可以 还通过家庭视频提供干预措施，如痴呆症护理计划。考虑到不断增长的使用和 数据库和相关技术的承诺，该提案将通过以下方式巩固和建立最新的进展 俄勒冈州阿尔茨海默病研究中心的数字技术核心(DTC)。具体目标是： 1.为了维持和提供研究，一个专门针对痴呆症的OADRC专注生活实验室 将在家中部署的研究志愿者队列(健康对照、MCI和AD) 最先进的传感和普适计算平台。 2.为获得和提供数据库关于OADRC主题的数据，以供研究使用。 3.促进涉及数据库及其相关技术的协作研究。

Project Summary: Digital Technology Core Given limitations of conventional clinical assessments to precisely map change trajectories, our research community increasingly seeks methodologies that incorporate continuous, real-world and objective measurement of key features (e.g., mobility, cognition, sleep, medication taking, driving) using the pervasive computing platform and methodologies of ORCATECH (Oregon Center for Aging & Technology). This new approach has important application in many areas of dementia research beyond early detection, such as caregiver/care recipient activities; agitation in institutional settings; and objective digital biomarkers (DB) of sleep, physical activity, and the environment. Use of these technologies is not limited to assessment, but may also deliver interventions, such as dementia care programs via home video. Given the growing use and promise of DB and related technologies, this proposal will consolidate and build upon recent advances through the Oregon Alzheimer’s Disease Research Center’s Digital Technology Core (DTC). Specific Aims are: 1. To maintain and make available for research, an OADRC dementia-specific focused Life Laboratory cohort of research volunteers (healthy controls, MCI, and AD) who will have deployed in their homes state-of-the-art sensing and pervasive computing platforms. 2. To obtain and make available for research, DB data on OADRC subjects. 3. To foster collaborative research involving DB and related technologies.