Unraveling the spread of antibiotic resistance genes across soil food webs

揭示抗生素抗性基因在土壤食物网中的传播

• 批准号: DP210100332
• 负责人: Dr Hangwei Hu
• 金额: $ 35.17万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-10-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210100332
• 关键词: Unraveling; spread; antibiotic; resistance; genes

The emerging spread of antibiotic resistance genes (ARGs) in the environment is a major threat to public health and food security. This project aims to develop new knowledge about the key transmission routes of ARGs across multiple trophic levels in soil food webs, and how the interactions of plant, soil and fauna contribute to the profiles of environmental ARGs. Expected outcomes include an improved understanding of the role of fauna in regulating ARGs in the soil environment and the spreading mechanisms of antibiotic resistance in soil food webs. This project will contribute to the development of evidence-based interventions to tackle environmental antibiotic resistance, which has benefits for the environment and public health.

抗生素抗性基因（ARG）在环境中的新传播对公共卫生和粮食安全构成了重大威胁。该项目旨在开发有关土壤食物网中多个营养级别的 ARG 关键传播途径的新知识，以及植物、土壤和动物之间的相互作用如何影响环境 ARG 的概况。预期成果包括更好地了解动物群在调节土壤环境中 ARG 的作用以及土壤食物网中抗生素耐药性的传播机制。该项目将有助于制定基于证据的干预措施，以解决环境抗生素耐药性问题，这对环境和公共卫生都有好处。