North American AIDS Cohorts Collaboration on Research and Design (NAACCORD) Renewal

北美艾滋病队列研究与设计合作（NA-ACCORD）是来自美国和加拿大的20个学术和社区前瞻性艾滋病毒研究队列的合作。这是北美最大的艾滋病毒群体合作，并已被证明是美国艾滋病毒流行的代表（根据疾病预防控制中心艾滋病毒监测报告）。紧急COVID-19问题可由NA-ACCORD联合调查人员使用以下数据回答：1)大规模艾滋病毒感染者（PWH）和非艾滋病毒感染者（PWOH）队列的现有数据；2)新建立的SARS-Cov-2检测人群（无论检测结果如何），每天都在招募参与者。NA-ACCORD研究人员将协同工作，共享数据收集工具、用于识别COVID-19疾病的算法和分析方法，以加快对多个数据源中的紧急问题的回答，并了解研究结果的异质性。

The North American – AIDS Cohort Collaboration on Research and Design (NA-ACCORD) is a collaboration of >20 academic and community-based prospective HIV research cohorts from the United States and Canada. It is the largest collaboration of HIV cohorts in North America and has been shown to be representative of the US HIV epidemic (according to CDC HIV Surveillance reports). Urgent COVID-19 questions can be answered by NA-ACCORD co-investigators using: 1) existing data in large-scale cohorts of people with (PWH) and without HIV (PWOH); and 2) newly established cohorts of people who have been tested for SARS-Cov-2 (regardless of the test result), which are enrolling participants every day. NA-ACCORD investigators will work collaboratively to share data collection instruments, algorithms for identifying COVID-19 disease, and analytic approaches to expedite answers to urgent questions in multiple data sources and understand the heterogeneity in findings. To answer urgent COVID-19 questions, this supplement will support: 1) assembling a team of experienced infectious disease epidemiologists and clinicians versed in longitudinal study design who are focused on answering urgent COVID-19 and understand heterogeneity in findings resulting from the same question being answered in different cohorts 2) the foundational steps to establishing 3 longitudinal COVID-19 clinical cohorts using EHR data 3) data management and analytic expertise specific to the profound health impacts of infectious disease using data from clinical (i.e. primarily EHR data) and interval cohort studies 4) establishing a library of COVID-19 surveys, person under investigation (PUI) forms, and other documentation forms from existing cohort studies, and providing a RedCap-based survey to NAACCORD cohorts in anticipation of future collaborative research 5) the development and sharing of EHR-based algorithms for COVID-19 and facilitating engagement with other groups working on common data models for COVID-19