The Johns Hopkins Center for AIDS Research (JHU CFAR)

约翰霍普金斯大学艾滋病研究中心 (JHU CFAR)

• 批准号: 10268586
• 负责人: Richard E. Chaisson
• 金额: $ 125.36万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-23 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10268586
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Area; Award; Baltimore; Behavioral; Biological Assay; Cities; Clinical; Clinical Research; Collaborations; Communities; Continuity of Patient Care; Data; Developing Countries; Development; Diagnosis; Discipline; Education and Outreach; Environment; Epidemic; Epidemiology; Esapent; Extramural Activities; Faculty; Fostering; Funding; Future; Generations; Goals; Grant; HIV; Health Occupations; Heart; Individual; Institution; Intervention; Intervention Studies; Investments; Laboratories; Lead; Leadership; Mentors; Mentorship; Minority Groups; Mission; NCI Scholars Program; Participant; Performance; Pilot Projects; Population; Productivity; Public Health Nursing; Reduce health disparities; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Support; Research Training; Resources; Schools; Science; Services; Social Justice; Specimen; Student recruitment; Students; Time; Training; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Universities; career; collaboratory; combat; community based evaluation; community setting; design; experience; graduate student; health disparity; innovation; interdisciplinary collaboration; medical schools; medical specialties; member; minority investigator; multidisciplinary; next generation; outreach; programs; recruit; research study; response; student participation; synergism; undergraduate student; virtual; working group

This is a competing renewal for the new Johns Hopkins University CFAR, initially funded in 2012. The new CFAR had a complete change in leadership, a major reorganization, a number of new and highly innovative approaches, and the enthusiastic and vigorous participation and support of the entire JHU HIV research community and the institution's leaders, who have contributed $2.25 million of additional support to fund additional developmental awards, student engagement, and outreach activities. For the past 4 years the CFAR has reinvigorated the HIV community at JHU, built thriving platforms through which interdisciplinary collaboration occurs, engaged new and junior investigators in cutting-edge research activities, provided vitally needed developmental resources for conducting pilot studies that lead to extramural funding, and contributed to the recruitment of new faculty, particularly 6 members of underrepresented minority groups. The CFAR has served over 373 HIV investigators, >130 NIH grants, and provided mentoring and assistance to 212 early stage investigators. Developmental Awards to early stage investigators or those new to HIV research have resulted in $57 million in new extramural awards, and our Internal Scientific Reviews of NIH applications have contributed to the funding of 14 new R01 or similar grants. The overall goal of this competing renewal application is to continue and enhance the ability of the Johns Hopkins University CFAR to nurture and support high-impact HIV research and researchers across a broad range of disciplines and specialties in the multiple divisions of this major research university. Our specific aims are 1) to enhance the integration and productivity of HIV/AIDS research by promoting inter-disciplinary innovation and collaboration; 2) to provide mentoring, support, and pilot funding for the next generation of HIV/AIDS researchers, with a commitment to recruiting researchers from underrepresented minority groups; 3) to support HIV/AIDS researchers with direct services to assist with recruitment of clinical research participants, performance of laboratory assays, design and analysis of research studies, and training in research methodologies; and 4) to mobilize and coordinate capacity from across JHU to combat the HIV epidemic in Baltimore through engagement, training, outreach, and evaluation of community-based intervention studies. The CFAR has 6 Cores and 3 Scientific Working Groups that provide services and support innovation in high-priority HIV research. The Baltimore HIV Collaboratory, and its Plan Baltimore 2020 project coordinate the JHU response to the local epidemic, orchestrating HIV research and outreach activities, and expanding the pipeline of future HIV researchers through the Baltimore HIV Scholars Program and Generation Tomorrow, initiatives aimed at students. The Provost and Deans of the 3 health professions schools at JHU have committed institutional funds of $2.7 million to support pilot awards, student recruitment, and Baltimore engagement. The CFAR will continue to have a galvanizing and transformative impact on HIV/AIDS research at JHU and we are delighted to submit this renewal application.

这是约翰霍普金斯大学新 CFAR 的竞争性更新，最初于 2012 年资助。 CFAR进行了领导层的彻底更迭、重大重组、多项具有高度创新性的新举措 方法以及整个约翰霍普金斯大学艾滋病毒研究的热情和积极参与和支持 社区和机构领导人为该基金提供了 225 万美元的额外支持 额外的发展奖项、学生参与和外展活动。过去 4 年 CFAR 重振了约翰霍普金斯大学的艾滋病毒社区，建立了蓬勃发展的平台，通过该平台进行跨学科研究 合作发生，让新的和初级研究人员参与前沿研究活动，提供了重要的 进行试点研究所需的发展资源，从而获得外部资金，并贡献了 招聘新教职人员，特别是 6 名代表性不足的少数群体成员。 CFAR 有 为超过 373 名 HIV 研究人员提供服务，获得超过 130 项 NIH 资助，并为 212 名早期研究人员提供指导和帮助 阶段调查员。为早期研究人员或艾滋病毒研究新手提供的发展奖 产生了 5700 万美元的新校外奖项，我们对 NIH 申请的内部科学审查 为 14 项新的 R01 或类似赠款提供了资金。本次竞争性更新的总体目标 申请是为了继续和增强约翰霍普金斯大学CFAR培养和支持的能力 跨多个学科和专业的高影响力艾滋病毒研究和研究人员 这所主要研究型大学的各个部门。我们的具体目标是 1) 增强集成度和生产力 通过促进跨学科创新和合作来开展艾滋病毒/艾滋病研究； 2）提供指导， 为下一代艾滋病毒/艾滋病研究人员提供支持和试点资金，并承诺招募 来自代表性不足的少数群体的研究人员； 3) 支持艾滋病毒/艾滋病研究人员提供直接服务 协助招募临床研究参与者、进行实验室测定、设计和分析 研究和研究方法培训； 4) 动员和协调各方的能力 整个约翰霍普金斯大学通过参与、培训、外展和评估来对抗巴尔的摩的艾滋病毒流行 以社区为基础的干预研究。 CFAR 有 6 个核心和 3 个科学工作组，提供 服务并支持高度优先的艾滋病毒研究创新。巴尔的摩艾滋病毒合作实验室及其计划 巴尔的摩 2020 项目协调约翰霍普金斯大学对当地流行病的应对措施，协调艾滋病毒研究和 外展活动，并通过巴尔的摩艾滋病毒学者扩大未来艾滋病毒研究人员的渠道 计划和明日一代，针对学生的举措。教务长和 3 卫生院院长 JHU 的职业学校已承诺提供 270 万美元的机构资金来支持试点奖项、学生 招聘和巴尔的摩参与。 CFAR 将继续发挥激励作用和变革作用 对约翰霍普金斯大学艾滋病毒/艾滋病研究的影响，我们很高兴提交这份更新申请。