Pilot Project Program

项目摘要 在过去的10年里，俄克拉荷马大学健康科学中心(OUHSC)科布雷 “指导俄克拉荷马州的糖尿病研究”已成为转型的重要资源 OUHSC成为致力于指导和发展初级调查人员的机构 为了富有成效的科学事业。通过支助9名初级调查员、7个试点项目和 这是一组不断发展的4核，该资源提供了基础架构，帮助推出了10多个 独立的研究事业，并支持随后资助许多地方和 国家拨款。此外，我们之前的许多Cobre试点项目都带来了新的 科布雷调查人员在俄克拉荷马州内外的合作。这些相互作用 在影响较大的期刊、新的科学方向和 跨实验室的技术转让。我们的试点项目选择过程需要一个开放的 竞赛(通知初级科学家、导师、科长和项目负责人)， 由我们经验丰富的内部咨询委员会对申请进行审查，对申请进行排名。 排名后的申请将由我们的外部咨询委员会进行审查，排名靠前的 在资源允许的情况下，为项目提供资金。所有申请者(无论他们是否获得资助) 收到有关应用程序的书面意见，并与 IAC至少有一名成员，以帮助改进未来提交的申请并 建议其他融资机会。所有试点项目获奖者出席并讨论他们的 与指定的指导团队一起取得进展，以及当前和讨论结果/未来 在选管会和选管会年度检讨上的指示。还对试点项目核心进行了评估 并通过《行政核心》概述的正式评价计划加以改进。在第三阶段， 由科布雷资助的试点项目将从副总统那里获得匹配资金 研究，进一步增强这一计划的影响。试点项目计划还将 与哈罗德·哈姆糖尿病中心资助的种子赠款计划联手。这 该计划将极大地促进俄克拉何马州的糖尿病研究，并为我们的申请做准备 美国国立卫生研究院资助的糖尿病研究中心。

Project Summary For the past 10 years, the University of Oklahoma Health Sciences Center (OUHSC) COBRE “Mentoring Diabetes Research in Oklahoma” has been an important resource in transforming OUHSC into an institution committed to the mentoring and development of junior investigators to productive scientific careers. Through its support of 9 junior investigators, 7 pilot projects, and an evolving set of 4 cores, this resource has provided the infrastructure to help launch over 10 independent research careers and support the subsequent funding of numerous local and national grants. In addition, many of our prior COBRE Pilot Projects have led to new collaborations between COBRE investigators within and outside Oklahoma. These interactions have led to collaborative manuscripts in high-impact journals, new scientific directions and transfer of technology across laboratories. Our Pilot Project selection process entails an open competition (with notifications to junior scientists, mentors, section chiefs and program heads), with applications reviewed by our experienced Internal Advisory Committee to rank applications. Ranked applications are then reviewed by our External Advisory Committee, and the top projects are funded as resources allow. All applicants (whether or not they receive funding) receive written comments about the application and have a post-review mentoring session with at least one member of the IAC to help improve the applications for future submissions and to suggest alternative funding opportunities. All Pilot Project awardees present and discuss their progress with an assigned mentoring team, as well as present and discuss results/future directions with the IAC and at the annual EAC review. The Pilot Project Core is also evaluated and improved through a formal evaluation plan outlined in the Administrative Core. In Phase III, the Pilot Projects funded by the COBRE will receive matching fund from the Vice President of Research, further enhancing the impacts of this program. The Pilot Project Program will also join force with the Seed Grant Program funded by the Harold Hamm Diabetes Center. This Program will greatly promote diabetes research in Oklahoma and prepare for our application for NIH-funded Diabetic Research Center.