Structural Birth Defects Meetings 12th-14th

科恩，DH 项目摘要 结构性出生缺陷是美国婴儿死亡的主要原因， 根据疾病控制中心的数据，大约有20%的婴儿死亡是由这种疾病造成的。受此影响 是结构性出生缺陷对公共卫生、社会经济地位 和家庭生活因此，尤尼斯·肯尼迪·施莱佛国家儿童研究所的主题1 健康和人类发展（NICHD）战略计划是“了解分子， 发展的细胞和结构基础”，最终目标是减少 结构性出生缺陷。更好地了解这些疾病及其原因， 改善成千上万出生时患有这种疾病的儿童的生活的重大承诺 美国每年的情况。为了进一步实现这一目标，近二十年来，科学家们一直在研究 结构性出生缺陷已经举行了11次会议（大约每两年），以描述 为支持该中心的这一使命而取得进展并开展合作。该提案将资助 2020年结构性出生缺陷会议和随后的两次会议。这些目标 会议是a）分享最近的，主要是未发表的研究结果，以了解原因， 结构性出生缺陷的诊断、治疗和预防; B）促进 基础科学家和医生科学家，促进结构性出生缺陷研究的未来进展; c）支持 培训和指导下一代结构性出生缺陷调查人员，包括 研究生、博士后研究员、住院医师和实习生- 会议期间的具体活动;以及d）支持代表人数不足的妇女参与 少数民族和残疾人通过参与结构性出生缺陷研究 在组织和举行会议方面提供资金，并提供出席会议的旅费赠款。 为期三天的会议将包括口头和海报介绍的研究人员资助下， 由NICHD和其他NIH研究所开发的程序以及来自 提交了摘要，两位主旨发言人就与会者广泛感兴趣的主题进行了演讲， 结构性出生缺陷研究的新方向的圆桌讨论，和五个实习生- 具体活动，以促进与外地领导人的互动。因此，第12 - 14届结构 出生缺陷会议将扩大NICHD和 结构性出生缺陷研究在社会上必不可少，前瞻性研究在这一重要 加速对这些疾病的生物学理解，以及治疗这些疾病的新方法。 为患者诊断和治疗。

Cohn, DH Project Abstract Structural birth defects are the leading cause of infant mortality in the United States, accounting for about 20% of all infant deaths according to the Centers for Disease Control. As a result there is a deep and lasting impact of structural birth defects on public health, socioeconomic status, and family life. Accordingly, Theme 1 of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Strategic Plan is “Understanding the Molecular, Cellular, and Structural Basis of Development”, with the ultimate goal of reducing the incidence of structural birth defects. A better understanding of these disorders and their causes holds substantial promise for improving the lives of the tens of thousands of children born with such conditions in the U.S. each year. To further this goal, for nearly two decades scientists studying structural birth defects have met eleven times (approximately every two years) to describe progress and develop collaborations in support of this NICHD mission. This proposal will fund the 2020 Structural Birth Defects Meeting and the subsequent two conferences. The goals of these meetings are a) to share recent, primarily unpublished research results to understand the causes, diagnosis, treatment and prevention of structural birth defects; b) to foster collaborations among basic and physician scientists for future progress in structural birth defects research; c) to support training and mentoring of the next generation of structural birth defects investigators including graduate students, postdoctoral fellows, and medical residents and fellows through trainee- specific events during the conference; and d) to support involvement of women, underrepresented minorities and individuals with disabilities in structural birth defects research through involvement in the organization and conduct of the conference and through travel grants to attend the meeting. The three day conference will include oral and poster presentations by investigators funded under programs developed by NICHD and other NIH Institutes as well as presentations derived from submitted abstracts, talks by two keynote speakers on topics of broad interest to the attendees, a roundtable discussion of new directions in structural birth defects research, and five trainee- specific events to foster interactions with leaders in the field. Consequently, the 12th-14th Structural Birth Defects Meetings will extend the critical role and strong track record of the NICHD and the structural birth defects research community in essential, forward-looking research in this important area, accelerating the biological understanding of these disorders and new approaches for diagnosis and treatment for patients.