Implementation Laboratory

实施实验室

• 批准号: 10225991
• 负责人: Lawrence N. Shulman
• 金额: $ 14.96万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10225991
• 关键词: Adherence; African American; Area; Biometry; Board Certification; Cancer Center; Cancer Control; Cancer Patient; Clinical; Clinical Informatics; Clinical Research; Clinical Services; Clinics and Hospitals; Collaborations; Communities; Community Practice; Computerized Medical Record; Consult; County Hospitals; Data; Data Analyses; Data Collection; Data Management Resources; Data Science; Data Security; Data Set; Data Storage and Retrieval; Databases; Delaware; Development; Doctor of Medicine; Ecosystem; Engineering; Ensure; Female; Future; General Hospitals; Gynecology; Head; Hematology; Hospitals; Informatics; Infrastructure; Internal Medicine; Laboratories; Latinx; Lead; Leadership; Link; Malignant Neoplasms; Medicaid; Medical; Medical center; Medicine; Methods; New Jersey; Oncologist; Oncology; Operative Surgical Procedures; Oral; Pathology; Patients; Pennsylvania; Pilot Projects; Population; Presbyterian Church; Protocols documentation; Radiation Oncology; Radiology Specialty; Research; Research Personnel; Resource Informatics; Resources; Sampling; Sampling Studies; Secure; Security; Selection Criteria; Services; Site; Standardization; Structure; System; Testing; Tobacco use; Training; Translational Research; Uninsured; Universities; University Hospitals; Wisconsin; Work; base; behavioral economics; cancer care; chemotherapy; clinical center; clinical research site; clinically relevant; community based practice; computer science; data dissemination; data management; data sharing; design; ethnic diversity; evidence base; experience; implementation science; implementation strategy; improved; innovation; interoperability; member; operation; patient population; programs; racial diversity; recruit; research study; scale up; socioeconomic diversity

The Implementation Laboratory (IL) for the University of Pennsylvania Implementation Science Center in Cancer Control (Penn ISC3) will provide the fundamental infrastructure, technical assistance, and leadership to ensure access to the populations needed to complete the planned and future studies within the Research Program and the informatics and data management organization to execute and complete these studies. The overall Director for the IL will be Lawrence N. Shulman, M.D., Deputy Director for Clinical Services of the Abramson Cancer Center (ACC) at Penn and Director of the Center for Global Cancer Medicine. He oversees strategic develop- ment of cancer services for the ACC and its affiliated hospitals and clinics (i.e., all members of the IL) and leads the Cancer Quality program for Penn Medicine, which oversees system-wide initiatives designed to improve the quality of cancer care. MPI Dr. Justin Bekelman will co-lead the IL with Dr. Shulman. The overarching objective of the IL will be to manage the diverse clinical sites that provide cancer care under Penn Medicine to ensure the successful completion of the planned and future studies in the Research Program and to oversee the Penn ISC3 informatics and data management infrastructure. Penn Medicine includes five hospitals (the Hospital of the Uni- versity of Pennsylvania, the Penn Presbyterian Medical Center, Pennsylvania Hospital, Chester County Hospital, and Lancaster General Hospital, and four community-based cancer practices (Regional Hematology Oncology Associates, Valley Forge Medical Center, Radnor Medical Center [staffed by clinicians from Pennsylvania Hos- pital], and Cherry Hill Medical Center). Within these 9 sites, there are over 200 clinicians that serve more than 15,000 new cancer patients annually. Since the Research Program will rely heavily on the electronic medical record (EMR) for implementation strategy delivery and data collection, the IL will also provide the leadership, technical assistance, and resources needed in clinical informatics. Dr. Peter Gabriel, Chief Oncology Informatics Officer (COIO) for Penn Medicine, and Associate Director for Data Science for the ACC, and his team will provide leadership, technical assistance, and resources for the Center’s clinical informatics needs, including the design and implementation of strategies implemented through the EMR and data collection through the EMR. Lastly, the IL will be comprised of data management support and resources under the direction of Ms. Sue Ware, the director of the Data Management Unit (DMU) for the Center. The DMU will provide systems for data collection, data storage and security, data management, provide datasets for biostatistical support and data sharing/dis- semination. Overall, the IL will ensure that the Penn ISC3 has the requisite leadership and access to the clinicians and patients to ascertain their study samples, has the needed clinical informatics support and resources to de- sign and execute the proposed implementation strategies through the EMR, and has the essential data manage- ment organization to ensure the complete and safe ascertainment of data for the proposed data analyses and dissemination. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page

宾夕法尼亚大学癌症实施科学中心实施实验室 (IL) Control (Penn ISC3) 将提供基本的基础设施、技术援助和领导力，以确保 接触完成研究计划内计划的和未来的研究所需的人群，以及 信息学和数据管理组织来执行和完成这些研究。总导演 IL 的负责人是医学博士 Lawrence N. Shulman，艾布拉姆森癌症临床服务副主任 宾夕法尼亚大学癌症中心 (ACC) 和全球癌症医学中心主任。他负责监督战略发展 为 ACC 及其附属医院和诊所（即 IL 的所有成员）提供癌症服务和领导 宾夕法尼亚大学医学院的癌症质量计划，该计划负责监督旨在改善癌症的全系统举措 癌症护理的质量。 MPI Justin Bekelman 博士将与 Shulman 博士共同领导 IL。总体目标 IL 的职责是管理 Penn Medicine 旗下提供癌症护理的不同临床中心，以确保 成功完成研究计划中计划的和未来的研究，并监督宾夕法尼亚大学 ISC3 信息学和数据管理基础设施。 Penn Medicine 包括五家医院（University of the Uni- 宾夕法尼亚大学、宾夕法尼亚长老会医疗中心、宾夕法尼亚医院、切斯特县医院、 和兰卡斯特总医院，以及四个基于社区的癌症诊所（区域血液肿瘤学 联营公司、Valley Forge 医疗中心、Radnor 医疗中心 [由来自宾夕法尼亚州霍斯-的临床医生组成 医院]和樱桃山医疗中心）。在这 9 个站点中，有超过 200 名临床医生，为超过 每年新增 15,000 名癌症患者。由于该研究计划将严重依赖电子医疗 实施策略交付和数据收集的记录（EMR），IL还将提供领导， 临床信息学所需的技术援助和资源。 Peter Gabriel 博士，首席肿瘤信息学 Penn Medicine 的官员 (COIO) 和 ACC 数据科学副主任，他的团队将提供 满足中心临床信息学需求的领导、技术援助和资源，包括设计 通过 EMR 实施战略并通过 EMR 收集数据。最后， IL 将在 Sue Ware 女士的指导下由数据管理支持和资源组成， 该中心数据管理部门（DMU）主任。 DMU 将提供数据收集系统， 数据存储和安全、数据管理，为生物统计支持和数据共享/发布提供数据集 授精。总体而言，IL 将确保 Penn ISC3 拥有必要的领导力并能够接触临床医生 和患者以确定他们的研究样本，拥有所需的临床信息学支持和资源来解决 通过 EMR 签署并执行拟议的实施策略，并拥有必要的数据管理能力 确保数据的完整和安全确定，以进行拟议的数据分析和 传播。 PHS 398/2590（修订版 06/09） 页面延续 格式页面