MPROS- MOBILE PRO-CTCAE ADMINISTRATION SYSTEM FOR POST-RADIATION TOXICITIES

MPROS- 辐射后毒性移动 PRO-CTCAE 管理系统

• 批准号: 10276304
• 负责人: JODY UNDERWOOD
• 金额: $ 150万
• 依托单位: INTELLIGENT AUTOMATION, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2022-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10276304
• 关键词: Area; Common Terminology Criteria for Adverse Events; Control Groups; Electronic Health Record; Intuition; Methods; Patient Outcomes Assessments; Patient Self-Report; Patients; Phase; Radiation; Radiation Toxicity; Randomized Clinical Trials; Reporting; Running; Severities; Structure; Symptoms; System; Testing; Time; chatbot; chemoradiation; commercialization; design; experience; experimental group; health related quality of life; improved; phase 2 study; programs; response; smartphone Application; symptom management; usability

mPROS is a patient-centric smartphone app which allows patients to comfortably report symptoms that are due to radiation and chemo-radiation treatment. mPROS provides clinicians with access to patient information that can be used to make timely treatment adjustments. Ultimately, mPROS will be integrated into Electronic Health Record (EHR) systems to make it seamless for clinicians to access patient-reported outcomes. It is hypothesized this individualized symptom reporting will improve patient health-related quality of life (HRQOL). The primary objective of the Phase II study is to demonstrate this benefit. Phase II will refine and improve the user experience and the content in mPROS and then run a randomized clinical trial to test its validity by showing that timely and individualized symptom reporting can result in better patient HRQOL.

mPROS是一款以患者为中心的智能手机应用程序，允许患者舒适地报告由于放疗和放化疗治疗引起的症状。mPROS为临床医生提供了访问患者信息的权限，这些信息可用于及时调整治疗。最终，mPROS将被集成到电子健康记录（EHR）系统中，使临床医生能够无缝访问患者报告的结果。据推测，这种个性化的症状报告将改善患者的健康相关生活质量（HRQOL）。II期研究的主要目的是证明这种益处。第二阶段将完善和改进mPROS中的用户体验和内容，然后进行随机临床试验，通过显示及时和个性化的症状报告可以改善患者的HRQOL来测试其有效性。