SEER-LINKED PEDIATRIC CANCER WHOLE SLIDE IMAGING PILOT, LOUISIANA STATE UNIV HEALTH SCIENCES CONTRACT HHSN261201800007I, POP 8/17/2020-8/16/2021

SEER-LINKED 儿科癌症全幻灯片成像试点，路易斯安那州立大学健康科学合同 HHSN261201800007I，POP 8/17/2020-8/16/2021

• 批准号: 10272830
• 负责人: XIAO-CHENG WU
• 金额: $ 17.99万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-17 至 2021-08-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10272830
• 关键词: Agreement; Algorithmic Analysis; Computer software; Contracts; Data; Development; Disease Outcome; Exercise; Funding; Goals; Health Sciences; Infrastructure; Laboratories; Link; Logistics; Louisiana; Malignant Childhood Neoplasm; Malignant Neoplasms; Metadata; Microscopic; Operative Surgical Procedures; Pathologist; Pathology; Phase; Reporting; Research; Signal Recognition Particle; Slide; Testing; Tissue Banks; Tumor Tissue; cancer diagnosis; digital; digital imaging; improved; microscopic imaging; treatment response; virtual; whole slide imaging

Project Abstract: The LTR has implemented electronic pathology (e-path) reporting at all pathology laboratories (except those with small cancer cases), covering over 95% of microscopically confirmed Louisiana cancer cases. We have also promulgated the legislative rules authorizing LTR to obtain tumor tissues for biospecimen research. Through the NCI-funded SEER-Linked Virtual Tissue Repository (VTR) study and supporting other biospecimen research, we have enhanced our infrastructures and exercised the ability to serve as an honest broker for biospecimen research, such as obtaining the necessary regulatory approval, retrieving required tumor tissues, and annotating them with cancer data. We are eager to take on this new opportunity to improve and expand further our capacity to support the development of automated digital image analysis algorithms to aid histomorphologic assessment by pathologists and examine associations between extracted microscopic features and disease outcome and response to treatments.

项目摘要：LTR已在所有病理实验室（小癌症病例除外）实施了电子病理学（e-path）报告，覆盖了路易斯安那州95%以上经显微镜确诊的癌症病例。我们还颁布了立法规则，授权LTR获取肿瘤组织用于生物样本研究。通过 NCI 资助的 SEER 链接虚拟组织存储库 (VTR) 研究和支持其他生物样本研究，我们增强了我们的基础设施，并锻炼了作为生物样本研究诚实经纪人的能力，例如获得必要的监管批准、检索所需的肿瘤组织并用癌症数据对其进行注释。我们渴望抓住这个新机会，进一步提高和扩展我们的能力，以支持自动数字图像分析算法的开发，以帮助病理学家进行组织形态学评估，并检查提取的微观特征与疾病结果和治疗反应之间的关联。