CHROME - Circadian Hypertension Rhythm Optimization Management Environment

Chrome背后的想法专注于自我驱动的健康。我们对Chrome的愿景是通过使用现有的CE标记的粘贴式设备来测量ECG，为建立与昼夜节律一致的血压提供单一解决方案。主要目标是建立与昼夜节律一致的血压，以便我们可以根据通常在7天内获取的60,480个读数提供个性化的高血压管理评分。重点是改进我们的算法，并开发一款应用程序，在现有的贴片硬件和智能手机之间建立接口，用于记录心电数据并执行我们的算法，将心电信号近乎实时地转换为收缩/舒张压读数，让佩戴者在不需要充气袖口的情况下获得接近真实的血压。这是一项创新，因为它允许我们使用现有的带有CE标志的硬件，该硬件具有蓝牙功能，但尚未被开发。为了扩展现有可穿戴设备的可用性。我们使用现有的粘贴式心电贴片，这是市场上最轻、最耐淋浴的设备，实时获取心电信号，并将10秒的时间序列的心电信号转换为血压。对于用户来说，这代表着他们血压数据的可访问性发生了相当大的变化，使他们能够看到自己的血压随时间变化的趋势，与他们的昼夜节律保持一致。这对个性化医学具有巨大的潜力，因为你第一次可以看到药物化合物对心电的影响，更重要的是血压。这可能是第一个允许用户了解血压控制药物(如β-受体阻滞剂或血管紧张素转换酶抑制剂)服用后的性能影响和时间反应的消费者系统。人们讨厌戴充气血压袖口，Chrome在无法接受血压袖口和智能手机健康监测之间架起了一座桥梁。Chrome是一项提案，将帮助我们发展我们的想法和业务，创造新的收入来源，提供证据和支持我们的市场，并帮助Circadian Dynamic Limited的资金和商业化计划。该项目有助于我们的商业道路，并为公司IP的潜力产生证据。

The idea behind CHROME focuses on self-driven healthcare.Our vision for CHROME is to provide a single solution for the establishment of Blood Pressure, aligned to Circadian Rhythm, through the use of an existing CE marked stick-on device that measures ECG.The key objectives are to establish the Blood Pressure aligned to the Circadian Rhythm, such that we can provide a personalised Hypertension management score based on typically 60,480 readings taken over a 7 day period, without the use of an inflatable cuff.The main area of focus is to refine our algorithm and to develop an app that interfaces between the existing stick-on patches hardware and a smartphone that can be used to record the ECG data and execute our algorithm to convert the ECG signal into a systolic/diastolic Blood Pressure reading in near-real time, giving the wearer of the device a near-real Blood Pressure, without the need for an inflatable cuff.This is innovative as it allows us to use an existing CE marked piece of hardware, that has Bluetooth functionality, but which has not been exploited, to create something that extends the usability of an existing wearable device.We use an existing stick-on ECG patch, the lightest, showerproof, device on the market, take the ECG signal from this in real-time and convert a 10 second time sequence of ECG signal into Blood Pressure.For the user, this represents a considerable step change in the accessibility of their Blood Pressure data, allowing them to see their BP trended over time, aligned to their Circadian Rhythm.This has enormous potential for personalised medicine as for the first time you can see the effect on pharmacological compounds on the both the ECG and more importantly the Blood Pressure. This is perhaps the first consumer system that allows users to understand the performance effects and time-response to the ingestion of Hypertension management drugs such as Beta-blockers or ACE inhibitors.People hate wearing inflatable Blood Pressure cuffs, CHROME bridges the gap between the unacceptability of Blood Pressure cuffs with the acceptability of smartphone health monitoring.CHROME is a proposal that will help us develop both our idea and our business, create a new revenue stream, provide evidence and enable our market, and help with the funding and commercialisation plans for Circadian Dynamics Limited.The project assists our commercial path and generates evidence of the potential for the company's IP.