Development of Line-Scan Temporal Focusing for fast structural imaging of synapse assembly/disassembly in vivo

开发线扫描时间聚焦，用于体内突触组装/拆卸的快速结构成像

• 批准号: 10301729
• 负责人: Josiah R Boivin
• 金额: $ 3.43万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2021-08-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10301729
• 关键词: Anesthesia procedures; Antibodies; Architecture; Brain; Brain Diseases; Cell Death; Color; Complex; Data; Development; Disease model; Event; Excitatory Synapse; Goals; Hour; Image; Individual; Inhibitory Synapse; Label; Methods; Microscopy; Molecular; Mus; Mutation; Neocortex; Nerve Degeneration; Neurodevelopmental Disorder; Neurons; Noise; Pharmaceutical Preparations; Physiological; Proteins; Proteome; Proteomics; Recording of previous events; Resolution; Sampling; Scaffolding Protein; Scanning; Side; Signal Transduction; Stains; Structure; Synapses; System; Technology; Time; Tissues; Visual Cortex; Visualization; design; feasibility testing; high resolution imaging; hippocampal pyramidal neuron; imaging approach; in vivo; in vivo imaging; microscopic imaging; neocortical; neuropsychiatric disorder; novel; preservation; protein complex; real time monitoring; recruit; synaptogenesis; two photon microscopy