Improving the Follow-up of Diabetic Patients by Measuring Earwax Glucose Concentration through a Self-Sampling Device

通过自采样装置测量耳垢葡萄糖浓度来改善糖尿病患者的随访

• 批准号: 10046928
• 金额: $ 3.83万
• 依托单位: TREARS LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10046928
• 关键词: Improving; Follow; up; Diabetic; Patients

_Trears biomarkers is on a mission to improve access to sustainable diagnostics. Trears is a patented diagnostic device, which can be used to non-invasively detect diabetes.__It is estimated that 415 million people are living with diabetes in the world, which is estimated to be 1 in 11 of the world's adult population. Adherence rates to diabetes testing among diabetes patients are very low. It has been found that up 51% of the diabetes patients, who were previously hospitalised declined an invitation to attend outpatient follow-up sessions after hospitalization_ _(Whitehouse FW et at. 1979)__. This group of patients had significantly higher hospital readmission rates than patients who were possible to follow up.__We found that Trears earwax glucose is 59% more predictable that HbA1c for estimating chronic glycaemia over a month. Trears test is cost effective, pain free, accurate and reliable (H__erane-Vives, A. et al 2021)__This project will be a critical step towards completion of the regulatory submission to enable commercialisation.__Herane-Vives, A. et al A Novel Earwax Self Sampling Device: A Feasibility Study Applied Sciences, 2021 - mdpi.com Appl. Sci. 2021, 11(11), 4882;_ _[https://doi.org/10.3390/app11114882][0]__Whitehouse FW, Whitehouse IJ, Smith J, et al. Teaching the person with diabetes: experience with a follow-up session. Diabetes Care. 1979; 2:35-38\._[0]: https://doi.org/10.3390/app11114882

_Trears生物标志物的使命是改善可持续诊断的可及性。Trears是一种专利诊断设备，可用于非侵入性检测糖尿病。据估计，世界上有4.15亿人患有糖尿病，估计占世界成年人口的1/11。糖尿病患者对糖尿病检测的依从率非常低。已经发现，之前住院的糖尿病患者中有高达51%拒绝了在住院后参加门诊随访会议的邀请（怀特豪斯FW et at.（1979年）。这组患者的再入院率明显高于可能随访的患者。我们发现，Trears耳垢葡萄糖比HbA 1c在估计一个月内的慢性高血糖症时更可预测59%。Trears测试是成本有效的，无痛的，准确和可靠的（H_erane-Vives，A.等2021）__该项目将是完成监管提交以实现商业化的关键一步。__ Herane-Vives，A.等人A Novel Earwax Self Sampling Device：A Feasibility Study Applied Sciences，2021 -mdpi.com Appl. Sci. 2021，11（11），4882;_ _[https：//doi.org/10.3390/app11114882][0]__怀特豪斯FW，怀特豪斯IJ，Smith J等人，糖尿病患者教学：随访会议的经验。糖尿病护理。1979; 2：35-38\._ [0]：https://doi.org/10.3390/app11114882网站