SToP Cancer SPORE: Administrative Core A

核心A：摘要 管理核心（核心A）支持SToP癌症孢子的工作。行政核心和 由叶博士领导的领导团队将负责所有人的战略规划、管理和承诺 项目和核心资源，并确保遵守所有大学，联邦和具体的NCI/NIH拨款 法规和要求，包括与国家癌症中心及时沟通和协商 院核心A将监督并促进与SPORE研究者和外部合作者的所有互动 给了莱恩伯格。此外，核心A将协调所有必要的会议，以管理方案 SPORE的运作，包括执行指导委员会、内部咨询委员会、 外部顾问委员会和SToP Cancer SPORE研究人员。通过这一系列会议， 承担对SPORE进行科学监督的责任，并将监督 发展研究和职业提升计划。这些功能将帮助孢子 领导正在进行的计划和评估，以确保实现进展 提出的目标，并解决出现的科学争议。核心A将协调所有人类主题研究- 遵守机构和联邦法规要求的相关活动。此外，核心A将 对SPORE承担总体财务责任，以确保资源的成本效益和有效利用，包括 对项目、基础设施和领导层招聘的大量机构承诺， 在SPORE的5年内接近750万美元。 通过这些活动，癌症孢子管理核心支持一个特殊的团队， 胰腺癌转化研究人员试图了解这种致命的疾病及其治疗方法， 推进新技术，并将初级教师培养成转化研究的领导者。

CORE A: ABSTRACT The Administrative Core (Core A) supports the work of this SToP Cancer SPORE. The Administrative Core and its leadership team led by Dr. Yeh will be responsible for strategic planning, management and commitment of all project and core resources, and ensuring compliance with all university, federal, and specific NCI/NIH grant regulations and requirements, including timely communications and consultations with the National Cancer Institute. Core A will oversee and facilitate all interactions with SPORE investigators and collaborators external to UNC Lineberger. Additionally, Core A will coordinate all necessary meetings to administer the programmatic operation of the SPORE, including meetings of the Executive Steering Committee, Internal Advisory Board, External Advisory Board, and SToP Cancer SPORE investigators. Through this series of meetings, the Core assumes responsibility for scientific oversight of the SPORE and will also oversee the activities of the Developmental Research and Career Enhancement Programs. These functions will assist the SPORE leadership in ongoing planning and evaluation of the program to ensure progress towards the accomplishment of the proposed aims and resolve scientific disputes that arise. Core A will coordinate all human subject research- related activities for compliance with institutional and federal regulatory requirements. In addition, Core A will have overall fiscal responsibility for the SPORE to ensure cost-effective and efficient use of resources, including the substantial institutional commitment to projects, infrastructure and recruitment allocated to leadership, which approaches $7.5M over the 5 years of the SPORE. Through these activities, the UNC SToP Cancer SPORE Administrative Core supports an exceptional team of pancreatic cancer translational researchers as they seek to understand this deadly disease and its treatment, advance new technology, and develop junior faculty into translational research leaders.