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中文摘要
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核心A:摘要 行政核心(核心A)支持这个阻止癌症孢子的工作。管理核心和 由叶博士领导的领导团队将负责战略规划、管理和所有 项目和核心资源,并确保遵守所有大学、联邦和特定的NCI/NIH拨款 条例和要求,包括及时与国家癌症中心进行沟通和磋商 研究所。核心A将监督和促进与孢子调查员和外部合作者的所有互动 致北卡罗来纳大学莱恩伯格分校。此外,核心A将协调所有必要的会议,以管理方案 孢子的运作,包括执行指导委员会、内部咨询委员会、 外部咨询委员会,以及停止癌症孢子调查。通过这一系列会议,核心 负责对孢子进行科学监督,并将监督 发展研究和职业提升计划。这些功能将帮助孢子 领导计划的持续规划和评估,以确保取得进展 建议的目标和解决出现的科学争议。核心A将协调所有人类主题研究- 为遵守机构和联邦法规要求而开展的相关活动。此外,核心A将 对孢子负有全面的财政责任,以确保具有成本效益和有效率地使用资源,包括 对分配给领导层的项目、基础设施和招聘的大量机构承诺, 在孢子生长的5年里,这笔钱接近750万美元。 通过这些活动,北卡罗来纳大学阻止癌症孢子管理核心支持一支特殊的团队 胰腺癌翻译研究人员试图了解这种致命的疾病及其治疗方法, 推进新技术,把初级教员培养成翻译研究带头人。
英文摘要
CORE A: ABSTRACT The Administrative Core (Core A) supports the work of this SToP Cancer SPORE. The Administrative Core and its leadership team led by Dr. Yeh will be responsible for strategic planning, management and commitment of all project and core resources, and ensuring compliance with all university, federal, and specific NCI/NIH grant regulations and requirements, including timely communications and consultations with the National Cancer Institute. Core A will oversee and facilitate all interactions with SPORE investigators and collaborators external to UNC Lineberger. Additionally, Core A will coordinate all necessary meetings to administer the programmatic operation of the SPORE, including meetings of the Executive Steering Committee, Internal Advisory Board, External Advisory Board, and SToP Cancer SPORE investigators. Through this series of meetings, the Core assumes responsibility for scientific oversight of the SPORE and will also oversee the activities of the Developmental Research and Career Enhancement Programs. These functions will assist the SPORE leadership in ongoing planning and evaluation of the program to ensure progress towards the accomplishment of the proposed aims and resolve scientific disputes that arise. Core A will coordinate all human subject research- related activities for compliance with institutional and federal regulatory requirements. In addition, Core A will have overall fiscal responsibility for the SPORE to ensure cost-effective and efficient use of resources, including the substantial institutional commitment to projects, infrastructure and recruitment allocated to leadership, which approaches $7.5M over the 5 years of the SPORE. Through these activities, the UNC SToP Cancer SPORE Administrative Core supports an exceptional team of pancreatic cancer translational researchers as they seek to understand this deadly disease and its treatment, advance new technology, and develop junior faculty into translational research leaders.
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Project 3: Transcriptomic subtypes, response predictions, and therapy selection
Project 3: Transcriptomic subtypes, response predictions, and therapy selection
Selective Targeting of Pancreatic Cancer SPORE
SToP Cancer SPORE: Administrative Core A
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