CEIRR: SARS-COV-2 Research Activities

CEIRR将确定影响SARS-CoV-2等呼吸道病毒进化、出现、传播和致病性的分子、生态和/或环境因素，并表征对感染的免疫反应，以提高对保护和交叉保护的免疫相关性的理解。CEIRR将开展一系列活动，包括队列研究以及人类和动物抽样，以进一步了解呼吸道感染、传播和疫苗接种；确定在对感染和疫苗接种的反应中决定疾病结局的免疫因素；以及确定冠状病毒如何在人类和物种间界面进化、适应和传播的研究。

CEIRR will determine the molecular, ecologic and/or environmental factors that influence the evolution, emergence, transmission and pathogenicity of respiratory viruses such as SARS-CoV-2, and characterize the immune response to infection to improve understanding of the immune correlates of protection and cross-protection. CEIRR will carry out a host of activities, including cohort studies and human and animal sampling to further understanding of respiratory infections, transmission and vaccination; identification of immunological factors that determine disease outcome in the response to infection and vaccination; and studies to determine how coronaviruses evolve, adapt and transmit between humans and at interspecies interfaces.