Pilot Project Program

项目摘要 试点项目计划（PPP）在追求辛辛那提大学的使命中发挥了关键作用。 环境遗传学中心（CEG），主题重点是基因-环境相互作用（GxE） research.公私营界别合作计划的整体目标，是为香港的新研究计划提供种子资助， 环境健康科学（EHS），这将揭示对CEG的GxE研究重点新的光。目标 是让调查人员，无论是建立或新的领域，以获得重要的初步数据，可以 成为新的NIH/NIEHS资助提案和相关出版物的基础。为了实现这一点， 将使用以下六种不同的奖励机制：新（早期）研究者奖，创新者奖， EHS新手调查员奖、Affinity Group奖、翻译和社区参与奖，以及 时间敏感响应奖。CEG-PPP依赖于对其试点项目的内部和外部审查 应用程序，并开发了一个跨中心评审员联盟，涉及四个NIEHS资助的P30 EHS 中心.审查过程与NIH遵循的格式密切一致。审查标准和 评分量表（1 - 9）类似于NIH的审查过程，使我们能够为申请人提供有意义的反馈， 并帮助该中心在NIH类型的审查过程中培训其初级教师。PPP具有内置的 通过定期进度报告跟踪试点奖励的进展和结果的机制 （包括专业介绍、出版物、校外赠款）和年度试点项目研讨会 针对CEG成员和大学校园的更广泛受众。总体而言，PPP 该计划是一个重要的工具，在多种方式，如帮助初级调查人员在他们的职业追求， 招募新的研究人员进入EHS研究领域，激发新的研究思路，填补空白 在CEG的研究议程中，促进设施核心的使用，建立跨学科的研究团队， 促进翻译和社区参与活动。从本质上讲，公私伙伴关系有助于整合所有其他 中心的组成部分，通过其奖励机制，并帮助个人CEG核心实现其 目标. CEG-PPP的绩效将继续由中心的内部咨询委员会进行审查 和外部咨询委员会，并根据两个关键标准进行判断： 校外资助和受资助的试点项目产生的出版物。CEP-PPP努力 保持其在引导试点资金到最有前途的项目在EHS和支持卓越 新的研究人员（早期和新的EHS），以促进获得新的和 GxE研究的创新方向。

PROJECT SUMMARY The Pilot Project Program (PPP) has played a key role in pursuing the mission of the University of Cincinnati's Center for Environmental Genetics (CEG) with a thematic focus on gene-environment interaction (GxE) research. The overall objective of the PPP is to provide seed support for new research initiatives in environmental health sciences (EHS) that will shed new light on the GxE research focus of the CEG. The goal is to allow investigators, either established or new to the field, to obtain significant preliminary data that can become the basis of new NIH/NIEHS grant proposal(s) and associated publications. To accomplish this, the following six different award mechanisms will be used: New (early stage) Investigator Award, Innovator Award, New-to-EHS Investigator Award, Affinity Group Award, Translation and Community Engagement Award, and Time-Sensitive Response Award. The CEG-PPP relies on both internal and external reviews of its pilot applications and has developed an Inter-Center Reviewer Consortium involving four NIEHS-funded P30 EHS Centers. The review process is aligned closely with the format followed at the NIH. Review criteria and the score scale (1-9) similar to NIH review process allow us to provide a meaningful feedback to the applicants as well as help the Center train its junior faculty in the NIH-type review process. The PPP has a built-in mechanism to track the progress and outcome of the pilot awards through a regular progress reporting (including professional presentations, publications, extramural grants) and an annual Pilot Project Symposium directed at a broader audience across the CEG membership and the university campus. Overall, the PPP program is an important vehicle in multiple ways such as helping junior investigators in their career pursuits, recruiting new investigators into the field of EHS research, stimulating novel research ideas and filling the gaps in CEG research agenda, promoting facility cores usage, building trans-disciplinary research teams and facilitating translation and community engagement activities. In essence, the PPP serves to integrate all other components of the Center through its award mechanisms, and helps the individual CEG cores realize their goals. The performance of the CEG-PPP will continue to be reviewed by the Center's Internal Advisory Board and External Advisory Board and judged by two key criteria: Return on Investment in terms of subsequent extramural funding and Publications emanating from the funded pilot projects. The CEP-PPP strives to maintain its excellence in channelizing the pilot funds to the most promising projects in EHS and supporting new investigators (both Early Stage and New-to-EHS) to facilitate obtaining extramural funding on new and innovative directions in GxE research.