Delaware INBRE

项目摘要-生物信息学核心 生物信息学现在在支持生物医学和所有生命科学研究方面发挥着核心作用;数据密集型 像RNA测序这样的研究方法已经成为基础技术。今天的研究人员必须 掌握这些技术如何推动他们的研究的概念。为了支持不断增长的 由于多样化的信息学需求，生物信息学核心必须发展，不仅提供计算基础设施， 执行高通量数据分析的专业知识，但也越来越多地作为教育驱动中心 培训精通信息的研究人员，他们可以有效地利用和解释数据。在建立了强大的 根据以前的DE-INBRE资助周期，特拉华州的生物信息学资源基金会 核心将进一步扩大其覆盖范围和影响整个国家。 DE-INBRE生物信息学核心组织为特拉华州生物信息学网络（BiND）， 该委员会包括来自所有合作机构的代表，以帮助指导和塑造特拉华州的INBRE 生物信息学倡议，并创造协同作用，以满足该计划不断变化的需求。特别是，DE-INBRE IV 将增加目前集中在特拉华州大学的生物信息学资源和专业知识的可及性 (UD)特拉华州州立大学（DSU）的生物成像和计算神经科学，以及生物医学和临床 信息学资源存放在Nemours/Alfred I。杜邦儿童医院（内穆尔）和克里斯蒂安娜护理 卫生系统（CCHS）在DE-INBRE伙伴机构提供信息网络基础设施， 研究支持，教育计划和研究曝光需要促进一个充满活力的生物医学研究 在特拉华州的能力。 具体目标 1.支持DE-INBRE扩大的生物医学研究网络。 2.提高特拉华州的生物医学研究能力。 3.支持特拉华州的生物医学研究计划。 4.提高特拉华州劳动力的科学技术知识。

Project Summary – Bioinformatics Core Bioinformatics now plays a central role in supporting research in biomedical and all life sciences; data-intensive research methodologies like RNA sequencing have become foundational techniques. The researchers of today must have a grasp of the concepts for how these technologies can advance their research. To support the growing and diversified informatics needs, bioinformatics cores have to evolve to not only provide computational infrastructure and the expertise to perform high-throughput data analysis, but also increasingly to serve as centers of education driving the training of informatically savvy researchers who can effectively utilize and interpret the data. Having built strong foundations for bioinformatics resources in Delaware under previous DE-INBRE funding cycles, the Bioinformatics Core will further expand its reach and impact throughout the State. The DE-INBRE Bioinformatics Core is organized as a Bioinformatics Network of Delaware (BiND) with a Steering Committee that includes representatives from all Partner Institutions to help guide and shape Delaware INBRE’s bioinformatics initiatives and create synergies to meet the evolving needs of the program. In particular, DE-INBRE IV will increase accessibility of bioinformatics resources and expertise currently concentrated at University of Delaware (UD), bio-imaging and computational neuroscience at Delaware State University (DSU), and biomedical and clinical informatics resources housed at Nemours/Alfred I. duPont Hospital for Children (Nemours) and Christiana Care Health System (CCHS) among the DE-INBRE Partner Institutions to provide the informatics cyberinfrastructure, research support, educational programs, and research exposures needed to promote a vibrant biomedical research capacity in the State of Delaware. Specific Aims 1. Support DE-INBRE’s expanded Biomedical Research Network. 2. Enhance Delaware’s biomedical research capacity. 3. Support biomedical research initiatives in Delaware. 4. Enhance the science and technology knowledge of Delaware’s workforce.