The Life And Death Of Plant Genes

我最近的工作表明，与动物基因不同，许多植物基因在物种内表现出存在/不存在的变异，并伴随着相关的性状变异。在这个项目中，我将通过比较十字花科植物的基因组来探索基因出生和死亡的模式，包括模式拟南芥和芥菜作物物种。通过比较许多基因组，我将了解新基因是如何诞生的。我将建立模型，根据基因的物理环境、功能和表达来预测基因丢失的可能性。该项目将建立在我们对植物遗传多样性的理解之上。这项研究的预期结果包括识别基因出生和丢失中的关键基因组元件，以及支持植物品种改良的策略。

My recent work has demonstrated that in contrast to animal genes, many plant genes show presence/absence variation within a species, with associated trait variation. In this project, I will explore models of gene birth and death by comparing genomes of Brassicaceae, including the model Arabidopsis and Brassica crop species. By comparing many genomes I will learn how new genes were born. I will build models that predict the likelihood of gene loss based on a gene’s physical environment, function, and expression. The project will build on our understanding of plant genetic diversity. Expected outcomes of this research include the identification of key genomic elements in gene birth and loss and support strategies to improve plant cultivars.