Administrative Core

管理核心摘要/摘要 行政核心的总体目标是最大限度地整合所有项目和核心， 项目研究人员和核心领导人之间的合作。这一核心对于协调 科学、财务、组织和监测活动，并促进项目间的相互作用 该多项目补助金的最大化，以最大限度地提高整个多项目研究计划的成功。的 核心将由伊丽莎白·贾菲博士领导，她在监督科学项目方面拥有丰富的经验。 在约翰霍普金斯的Sidney Kimmel癌症中心，以及NIH资助的一些多项目 程序. Jaffee博士最近担任一个多中心、多个主要研究者的团队负责人 通过Stand Up To Cancer。丹尼尔拉赫鲁博士将担任该核心的共同领导人。Laheru博士 带来了多年的胰腺癌临床试验经验， 胃肠道癌症项目主任和Skip Viragh胰腺癌项目联合主任 临床研究和临床护理中心。 具体目标是：1）提供组织和行政管理，以确保成功 项目内的所有项目和核心; 2）促进科学合作和项目 通过协调科学和咨询委员会会议进行监督， 程序. Drs. Jaffee和Laheru将监控所有项目和核心的进展，确定挑战或障碍， 并协助解决问题。Jaffee和Laheru博士的行政助理将 负责监督各项目资金的分配和使用情况 和核心。她还将提供该计划内所有项目和核心的月度财务报告， 协助研究者进行非竞争性更新申请，并为手稿提供支持 准备和提交。 Drs. Jaffee和Laheru将每周为项目的所有成员召开科学会议， 项目和核心领导人的月度会议，以确保项目和核心领导人之间的充分沟通， 整合所有项目和核心团队。还将每季度与内部 顾问委员会负责监察小组的科学进展，并提供意见。此外还将有 一年一度的为期一天的科学务虚会，包括所有研究人员和内部和外部的科学 顾问。顾问务虚会结束时将举行一次顾问委员会闭门会议 向项目调查人员提供客观反馈。

Administrative Core Summary/Abstract The overall goal of the Administrative Core is to maximize integration of all projects and cores, and collaborations among Program Investigators and Core leaders. This Core is essential for coordinating the scientific, financial, organizational, and monitoring activities, and facilitating inter-project interactions of this multi-project grant to maximize the success of the overall multi-project research program. The Core will be led by Dr. Elizabeth Jaffee, who has extensive experience overseeing scientific programs at the Sidney Kimmel Cancer Center at Johns Hopkins, as well as a number of multi-project NIH funded programs. Dr. Jaffee recently served as the Team Leader for a multi-site, multiple principal investigator grant through Stand Up To Cancer. Dr. Daniel Laheru will serve as co-leader of this Core. Dr. Laheru brings many years of experience conducting clinical trials in pancreatic cancer and serves as the co- director of the Gastrointestinal Cancer program and co-director of the Skip Viragh Pancreatic Cancer Center for Clinical Research and Clinical Care. The specific aims are to: 1) Provide organizational and administrative management to insure success of all projects and cores within the program; and 2) Facilitate scientific collaborations and program oversight through the coordination of scientific and advisory board meetings for the investigators in this program. Drs. Jaffee and Laheru will monitor progress of all Projects and Cores, identify challenges or hurdles, and assist with problem solving. The Administrative Assistant to Drs. Jaffee and Laheru, will be responsible for oversight of the distribution and usage of funding provided to the individual programs and Cores. She will also provide monthly financial reports for all projects and cores within the program, assist investigators with non-competitive renewal applications, and provide support for manuscript preparation and submission. Drs. Jaffee and Laheru will convene weekly scientific meetings for all members of the Program Project, and monthly meetings of Project and Core Leaders to ensure adequate communication between and integration of all Project and Core teams. There will also be quarterly meetings with the internal advisory board to monitor and provide input on the group’s scientific progress. In addition, there will be an annual one-day scientific retreat to include all investigators and the internal and external scientific advisors. A closed advisory board meeting will be held at the conclusion of the retreat for the advisors to provide objective feedback to the program investigators.