Chemistry-Biology Interface T32

化学-生物接口 T32

• 批准号: 10409763
• 负责人: Jennifer J Kohler
• 金额: $ 16.12万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10409763
• 关键词: Biology; Chemistry

UT Southwestern Medical Center (UTSW) has a long institutional history of valuing and promoting collaborative science, and provides a unique environment for chemistry and biochemistry graduate students to participate in interdisciplinary education and research. This proposal embodies the culture of UTSW and outlines a new predoctoral training program dedicated to providing interdisciplinary training at the Chemistry- Biology Interface (CBI). Organized with a Drug Discovery mindset, our training program equips young scientists with the fundamental knowledge and interdisciplinary skills that are needed to tackle challenging diverse problems in biomedical research and to identify new areas of opportunity. As a guiding principle, we believe that building a strong and diverse biomedical workforce requires developing excellence in individual disciplines while fostering collaborative efforts among experts in disparate fields. Students complete rigorous graduate training in either chemistry or biology, while also developing broad knowledge of the most important principles and problems in both fields. The CBI at UTSW program is designed to meet three objectives: First, students will become experts in their individual fields of chemistry or biology. Second, students will be knowledgeable about the most important principles and problems in both fields. Finally, students will be skilled in communicating scientific challenges and discoveries to a wide range of individuals, from experts to laypeople. The CBI program will directly support two students each during years 2 and 3 of their predoctoral training and will also train McKnight fellows who are supported by UTSW through private funds; all trainees will continue to benefit from CBI resources until graduation. The program will capitalize on its setting within a leading medical center to offer training activities that focus on preclinical Drug Discovery. The training faculty members for the CBI program are part of a rich network of collaborations that scaffold the training program, but also extend throughout the University and into the larger scientific community. Together, these training aspects are designed to provide students with the scientific knowledge and collaborative prowess to work together in an interdisciplinary team to address the most compelling and intractable scientific questions, with the goal of developing the next generation of biomedical researchers. “Value-added” features of the UTSW CBI training program include: (a) an advanced course in Drug Discovery taught by experts in academia and industry; (b) an improved Enzymes and Disease course that facilities interdisciplinary and collaborative science through peer-led team learning; (c) personalized instruction in scientific writing, specifically aimed at funding opportunities; (d) training in scientific communication through coached production of ScienceSketch YouTube videos; (e) trainee-designed participation in mini-sabbaticals to enhance cross-disciplinary and non-academic training; (f) monthly meetings between CBI trainees and faculty advisory committee that offer collegial support and career enrichment opportunities; and (g) support for teaching and outreach activities.

UT西南医学中心（UTSW）有着悠久的重视和促进 协作科学，并为化学和生物化学研究生提供了一个独特的环境， 参与跨学科的教育和研究。该提案体现了UTSW的文化， 概述了一个新的博士前培训计划，致力于在化学提供跨学科的培训- 生物学接口（CBI）。我们的培训计划以药物发现的心态组织， 科学家的基本知识和跨学科的技能，需要解决挑战 生物医学研究中的各种问题，并确定新的机会领域。作为指导原则，我们 我认为，建立一个强大的和多样化的生物医学劳动力需要发展卓越的个人 同时促进不同领域专家之间的合作努力。学生完成严谨 在化学或生物学的研究生培训，同时也发展最重要的广泛知识， 这两个领域的原则和问题。UTSW的CBI计划旨在实现三个目标：首先， 学生将成为化学或生物学领域的专家。第二，学生将 了解这两个领域中最重要的原则和问题。最后，学生将 善于将科学挑战和发现传达给各种各样的人，从专家到 外行人CBI计划将直接支持两名学生在第2年和第3年的博士前 培训，也将培训麦克奈特研究员谁是支持UTSW通过私人基金;所有学员 将继续受益于CBI资源，直到毕业。该计划将利用其设置在一个 领先的医疗中心提供培训活动，重点是临床前药物发现。培训学院 CBI项目的成员是一个丰富的合作网络的一部分，该网络支撑了培训项目， 而且还延伸到整个大学和更大的科学界。这些培训， 方面的目的是为学生提供科学知识和协作能力的工作 在一个跨学科的团队，以解决最引人注目的和棘手的科学问题， 培养下一代生物医学研究人员的目标。UTSW CBI的“增值”功能 培训计划包括：（a）由学术界专家讲授的药物发现高级课程， （B）改进酶和疾病课程，促进跨学科和协作科学 通过同侪领导的团队学习;（c）个性化的科学写作指导，特别是针对资助 机会;（d）通过指导制作ScienceSketch YouTube进行科学传播培训 （e）受训人员参加设计的小型休假，以加强跨学科和非学术性的培训， 培训;（f）CBI受训人员与提供学院支持的教师咨询委员会之间的每月会议 和职业充实机会;以及（g）支持教学和外联活动。