High-Energy Tunable Nanosecond-Pulsed Laser

所要求的仪器是一台高能宽可调纳秒脉冲激光器。 由Opotek LLC制造。这台仪器将作为宽幅阵列的激励源 纳秒时间分辨瞬变光谱(发光、紫外可见吸收、 FTIR、共振拉曼)以及用于稳态拉曼光谱的激发源。 激光将被安置在贝克曼研究所激光资源中心，该设施专注于 为加州理工学院的研究团体提供稳定状态下的仪器和指导 和时间分辨激光光谱学、常规光谱学、光物理和 光化学。该中心的一个主要焦点是用于测量的时间分辨光谱学 化学和生化动力学，以及化学反应机理的阐明。这个 激光将为NIH资助的三个主要用户的研究项目提供必要的支持，如 以及其他用户的三个外部资助和三个内部资助的研究计划。 美国国立卫生研究院资助的项目包括：铁和铜中自由基转移途径的研究 加氧酶和加氧酶.铜基光化学机理的阐明 参与(对映选择性)C-N键形成的催化剂；机理研究 生物启发铁模型络合物催化的氮素还原化学；以及 DNA介导的铜绿假单胞菌电荷转移过程的研究 生物膜。利用该仪器的其他研究项目将涉及：机械性调查 裂解多糖单加氧酶的催化作用；光物理研究 芳基异氰酸酯-金属络合物.软到硬x-2用台式等离子体源的研制 射线；光氧化还原机理的时间分辨光谱表征；以及时间- 单重态产生的双并五苯三重态的分辨光谱表征 裂变。

The requested instrument is a high-energy broadly tunable nanosecond-pulsed laser manufactured by Opotek LLC. This instrument will serve as an excitation source for a wide array of nanosecond time-resolved transient spectroscopies (luminescence, UV-Visible absorption, FTIR, resonance Raman) as well as an excitation source for steady-state Raman spectroscopy. The laser will be housed in the Beckman Institute Laser Resource Center, a facility focused on providing the Caltech research community with instrumentation and guidance in steady-state and time-resolved laser spectroscopy, conventional spectroscopy, photophysics, and photochemistry. A primary focus of the Center is time-resolved spectroscopy for measurements of chemical and biochemical kinetics, and the elucidation of chemical reaction mechanisms. The laser will furnish essential support for three NIH-funded research programs of Major Users, as well as three externally funded and three internally funded research programs of Other Users. The NIH-funded programs include: studies of radical transfer pathways in iron and copper oxygenases and oxidases; elucidation of the photochemical mechanisms of copper-based catalysts involved in (enantioselective) C–N bond formation; mechanistic investigations of dinitrogen reduction chemistry catalyzed by bioinspired iron model complexes; and investigations of DNA mediated charge transfer processes in Pseudomonas aeruginosa biofilms. Other research projects utilizing the instrument will address: mechanistic investigations of lytic polysaccharide monooxygenase catalysis; photophysical investigations of arylisocyanide-metal complexes; development of table-top plasma sources for soft to hard x- rays; time-resolved spectroscopic characterization of photoredox mechanisms; and time- resolved spectroscopic characterization of bipentacene triplet states generated via singlet fission.