High-Energy Tunable Nanosecond-Pulsed Laser

所要求的仪器是高能量宽调谐纳秒脉冲激光器 由Opotek LLC制造。这台仪器将作为一个激发源， 纳秒时间分辨瞬态光谱（发光，紫外-可见吸收， FTIR、共振拉曼）以及用于稳态拉曼光谱的激发源。 该激光器将被安置在贝克曼研究所激光资源中心，该中心专注于 为加州理工学院的研究社区提供稳定状态下的仪器和指导， 和时间分辨激光光谱学，传统光谱学，光物理学， 光化学该中心的一个主要重点是时间分辨光谱测量 化学和生物化学动力学，以及化学反应机理的阐明。的 激光将为NIH资助的三个主要用户研究项目提供必要的支持， 以及其他用户的三个外部资助和三个内部资助的研究项目。 美国国立卫生研究院资助的项目包括：铁和铜的自由基转移途径的研究 加氧酶和氧化酶.铜基 （对映选择性）C-N键形成的催化剂; 由生物启发的铁模型络合物催化的二氮还原化学;以及 铜绿假单胞菌DNA介导电荷转移过程的研究 生物膜利用该仪器的其他研究项目将解决： 溶解性多糖单加氧酶催化的物理化学研究 芳基异氰-金属络合物;软到硬x-射线的台式等离子体源的发展 射线;光氧化还原机制的时间分辨光谱表征;和时间- 通过单线态产生的并五苯三重态的分辨光谱表征 裂变

The requested instrument is a high-energy broadly tunable nanosecond-pulsed laser manufactured by Opotek LLC. This instrument will serve as an excitation source for a wide array of nanosecond time-resolved transient spectroscopies (luminescence, UV-Visible absorption, FTIR, resonance Raman) as well as an excitation source for steady-state Raman spectroscopy. The laser will be housed in the Beckman Institute Laser Resource Center, a facility focused on providing the Caltech research community with instrumentation and guidance in steady-state and time-resolved laser spectroscopy, conventional spectroscopy, photophysics, and photochemistry. A primary focus of the Center is time-resolved spectroscopy for measurements of chemical and biochemical kinetics, and the elucidation of chemical reaction mechanisms. The laser will furnish essential support for three NIH-funded research programs of Major Users, as well as three externally funded and three internally funded research programs of Other Users. The NIH-funded programs include: studies of radical transfer pathways in iron and copper oxygenases and oxidases; elucidation of the photochemical mechanisms of copper-based catalysts involved in (enantioselective) C–N bond formation; mechanistic investigations of dinitrogen reduction chemistry catalyzed by bioinspired iron model complexes; and investigations of DNA mediated charge transfer processes in Pseudomonas aeruginosa biofilms. Other research projects utilizing the instrument will address: mechanistic investigations of lytic polysaccharide monooxygenase catalysis; photophysical investigations of arylisocyanide-metal complexes; development of table-top plasma sources for soft to hard x- rays; time-resolved spectroscopic characterization of photoredox mechanisms; and time- resolved spectroscopic characterization of bipentacene triplet states generated via singlet fission.