Development Research Program

发展研究计划：项目摘要/摘要 黑色素瘤中的孢子发展研究计划(DRP)用于确定和资助试点项目 最大限度地利用新的研究突破和新颖的想法，这些最终可能会减少 黑色素瘤的发病率和发病率或增加患者的存活率。对……的认识进展 黑色素瘤的生物学和免疫反应在黑色素瘤患者预后中的作用已导致大量 针对黑色素瘤患者的靶向和免疫治疗的进展，前景看好 近期的未来进展。因此，我们对利用来自 在这一DRP方面拥有各种专业知识的研究人员，并为测试创造性假设提供种子资金 以及获取没有得到当前或替代资金来源支持的项目的初步数据。 高风险/高回报试点项目特别优先，妇女和少数族裔或 服务不足的调查人员受到强烈鼓励。DRP可用的资金包括所需的50,000美元 在孢子奖有效期内每年，以及每年最高100,000美元的捐款 来自机构的“配对基金”，每年总计15万美元。现正征集孢子防腐剂的申请 每年，目标是资助至少3个一年期奖项，每个奖项最高可达50,000美元，并有可能持续 如果根据可接受的进展提出请求并获得批准，则支持第二年50,000美元的奖励。 如果可以的话，慈善基金也将用于支持高质量的提案。可提供 为主要孢子项目或支持其他新黑色素瘤或并发黑色素瘤提供额外价值的“管道” 欢迎拨款。

Developmental Research Program: Project Summary/Abstract This SPORE in Melanoma Developmental Research Program (DRP) serves to identify and fund pilot projects that take maximum advantage of new research breakthroughs and novel ideas that may eventually reduce the incidence and morbidity or increase the survival of patients with melanoma. Progress in understanding of melanoma biology and the role of immune response in melanoma patient outcomes has led to substantial advances in both targeted and immunotherapies for melanoma patients, and much promise is held for immediate future advances. Therefore, we are particularly interested in leveraging novel ideas from investigators with a variety of expertise in this DRP, and providing seed money for testing creative hypotheses and obtaining preliminary data for projects that are not supported by current or alternative funding sources. High risk/high reward pilot projects are especially prioritized, and applications from women and minority or underserved investigators are strongly encouraged. The available DRP funds include the required $50,000 annually throughout the duration of the SPORE award, as well as an annual contribution of up to $100,000 from institutional “matching funds,” for a total of $150,000 per year. Applications for SPORE DRPs are solicited annually, with an aim to fund at least 3 one-year awards of up to $50,000 each, with the possibility of ongoing support for a second year award of $50,000 if requested and approved based on acceptable progress. Philanthropic funds will also be utilized if available to support high quality proposals. Projects that provide a “pipeline” of additional value to the main SPORE projects or that support other new or concurrent melanoma grants are welcomed.