Molecular Biophysics Training Program

摘要 新的实验和计算/理论生物物理方法迅速发展。 最近，将分子生物物理领域置于推动未来生物医学重大进展的地位 科学。该提案描述了德克萨斯大学西南分校的分子生物物理培训计划，该计划将培训一名 新一代生物物理学家掌握新的标准生物物理方法，分析和解释 复杂的数据集，以严格和可重现的方式。该计划旨在发展一种广泛的 了解生物学，让我们的学员使用分子生物物理学的进展来回答最 重要的生物医学问题。随着研究变得更加复杂，研究人员必须进行有效的沟通， 无论是在跨学科研究团队内部还是在公众面前。量化的生物物理研究人员也将 需要代表整个社会。这项建议旨在培养不同的生物物理实习生群体， 成为生物医学劳动力领军者的技能广度。我们将通过以下方式实现这些目标： 通过结合物理原理和方法的严格课程进行高质量的研究培训 从科学和数学到细胞和分子生物学的研究。我们将教学生变得熟悉 并能够有效和批判性地交流研究成果，如 在正在进行的工作研讨会、杂志俱乐部、分子生物物理讨论小组或 MBDG系列研讨会和年度研究研讨会。针对T32任命者的强化培训将 包括年度咨询会议和小型研讨会，以及在MBDG和研究中的独特机会 研讨会。学员将从跨学科的分子生物物理学研究生计划中挑选出来，该计划 拥有来自许多不同部门和中心的教员，使培训计划能够从 研究生课程的资源。然而，培训计划的结构也是根据受训者的需求而发展的 因为他们驾驭着一个不断变化的科学和专业版图。我们申请资助6名博士后 每年都有空档来执行培训计划的使命和目标。目前有26个培训补助金 26名参与项目教员的实验室中符合条件的学生，他们有充足的资金和研究项目 跨越跨学科的生物物理方法，提供不同的、互补的方法 各种重要的生物医学问题。在过去的10年里，教职员工总共培训了58名学生 他们93%的毕业生仍在理工科。培训计划是独一无二的(与其他T32的重叠最小 作为参与的教员，他们通过使用生物物理方法而团结在一起。质量和质量 生源数量多，参训师资力量雄厚，科研力量多样，资金雄厚 项目组合，以及培训计划重点的独特性，构成了这个分子课程坚实的基础 生物物理学培训计划建议书。 好了！

Abstract New experimental and computational/theoretical biophysical approaches have been developed at a rapid pace recently, placing the field of Molecular Biophysics in a position to drive future major advances in biomedical sciences. This proposal describes a Molecular Biophysics Training Program at UT Southwestern that will train a next generation of biophysicists to master new and standard biophysical approaches, analyze and interpret complex sets of data, in rigorous and reproducible manners. The Program aims to develop a broad understanding of biology, to allow our trainees to use molecular biophysical advances to answer the most important biomedical questions. As research becomes more complex, researchers must communicate effectively, both within interdisciplinary research teams and to a lay public. Quantitative biophysical researchers will also need to represent society in general. This proposal aims to develop a diverse group of biophysical trainees with the breadth of skills to become leaders across the biomedical workforce. We will achieve these goals by providing high quality research training through a rigorous curriculum that couples principles and methods of physical sciences and mathematics to studies of cell and molecular biology. We will teach students to become conversant with the scientific literature and be able to effectively and critically communicate research findings, as implemented in Works In Progress seminars, Journal Clubs, the Molecular Biophysics Discussion Group or MBDG seminar series and a yearly research symposium. Enhanced training specific to T32 appointees will include annual Advisory Meeting and Mini-Symposium, and unique opportunities within the MBDG and research symposium. Trainees will be drawn from the interdisciplinary Molecular Biophysics Graduate Program, which has faculty from many different Departments and Centers, allowing the Training Program to draw from the Graduate Program’s resources. The Training Program is, however, also structured to evolve with trainees’ needs as they navigate an ever-changing scientific and professional landscape. We request funding for 6 predoctoral slots each year to pursue the mission and goals of the Training Program. There are currently 26 training grant eligible students in the labs of 26 participating program faculty, who are well-funded and have research portfolios cross the spectrum of interdisciplinary, biophysical methods, providing different, complementary approaches to a variety of important biomedical questions. Collectively, the faculty have trained 58 students in the past 10 years; 93% of their graduates still in science. The training program is unique (minimal overlap with other T32 programs on campus) as participating faculty are united by their use of biophysical methods. The quality and quantity of students, the participating faculty with strong training records, diverse and well-funded scientific portfolios, and the uniqueness of the training program’s focus form a rock-solid foundation for this Molecular Biophysics Training Program proposal. !