Molecular Biophysics Training Program

分子生物物理学培训计划

• 批准号: 10421305
• 负责人: Yuh Min Chook
• 金额: $ 24.11万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10421305
• 关键词: Biophysics; Molecular; Training Programs

Abstract New experimental and computational/theoretical biophysical approaches have been developed at a rapid pace recently, placing the field of Molecular Biophysics in a position to drive future major advances in biomedical sciences. This proposal describes a Molecular Biophysics Training Program at UT Southwestern that will train a next generation of biophysicists to master new and standard biophysical approaches, analyze and interpret complex sets of data, in rigorous and reproducible manners. The Program aims to develop a broad understanding of biology, to allow our trainees to use molecular biophysical advances to answer the most important biomedical questions. As research becomes more complex, researchers must communicate effectively, both within interdisciplinary research teams and to a lay public. Quantitative biophysical researchers will also need to represent society in general. This proposal aims to develop a diverse group of biophysical trainees with the breadth of skills to become leaders across the biomedical workforce. We will achieve these goals by providing high quality research training through a rigorous curriculum that couples principles and methods of physical sciences and mathematics to studies of cell and molecular biology. We will teach students to become conversant with the scientific literature and be able to effectively and critically communicate research findings, as implemented in Works In Progress seminars, Journal Clubs, the Molecular Biophysics Discussion Group or MBDG seminar series and a yearly research symposium. Enhanced training specific to T32 appointees will include annual Advisory Meeting and Mini-Symposium, and unique opportunities within the MBDG and research symposium. Trainees will be drawn from the interdisciplinary Molecular Biophysics Graduate Program, which has faculty from many different Departments and Centers, allowing the Training Program to draw from the Graduate Program’s resources. The Training Program is, however, also structured to evolve with trainees’ needs as they navigate an ever-changing scientific and professional landscape. We request funding for 6 predoctoral slots each year to pursue the mission and goals of the Training Program. There are currently 26 training grant eligible students in the labs of 26 participating program faculty, who are well-funded and have research portfolios cross the spectrum of interdisciplinary, biophysical methods, providing different, complementary approaches to a variety of important biomedical questions. Collectively, the faculty have trained 58 students in the past 10 years; 93% of their graduates still in science. The training program is unique (minimal overlap with other T32 programs on campus) as participating faculty are united by their use of biophysical methods. The quality and quantity of students, the participating faculty with strong training records, diverse and well-funded scientific portfolios, and the uniqueness of the training program’s focus form a rock-solid foundation for this Molecular Biophysics Training Program proposal. !

摘要 新的实验和计算/理论生物物理方法已经迅速发展 最近，将分子生物物理学领域置于推动生物医学未来重大进展的位置， 以理工科为重该提案描述了UT西南大学的分子生物物理学培训计划，该计划将培训 下一代生物物理学家掌握新的标准生物物理方法，分析和解释 复杂的数据集，以严格和可重复的方式。该计划旨在发展一个广泛的 生物学的理解，让我们的学员使用分子生物物理学的进步，以回答最 重要的生物医学问题。随着研究变得越来越复杂，研究人员必须有效地沟通， 无论是在跨学科的研究团队和外行公众。定量生物物理研究人员也将 必须代表整个社会。这项建议旨在培养一批多样化的生物物理学受训人员， 技能的广度，成为整个生物医学劳动力的领导者。我们将通过提供 高质量的研究培训，通过严格的课程，夫妇的原则和方法的物理 科学和数学的细胞和分子生物学研究。我们将教学生变得熟悉 与科学文献，并能够有效地和批判性地交流研究成果， 在正在进行的研讨会，期刊俱乐部，分子生物物理讨论组或 MBDG系列研讨会和年度研究研讨会。针对T32任命人员的强化培训将 包括年度咨询会议和小型研讨会，以及MBDG和研究中的独特机会 研讨会学员将从跨学科的分子生物物理学研究生课程， 拥有来自许多不同部门和中心的教师，使培训计划能够从 研究生课程的资源。然而，培训方案的结构也随着受训者的需要而变化 因为他们在不断变化的科学和专业领域中航行。我们申请资助6名博士生 以实现培训计划的使命和目标。目前有26个培训补助金 26名参与计划的教师的实验室中符合条件的学生，他们资金充足，拥有研究组合 跨学科，生物物理方法的频谱，提供不同的，互补的方法， 一系列重要的生物医学问题。在过去的10年里，教师们总共培训了58名学生。 年; 93%的毕业生仍然在科学。培训计划是独一无二的（与其他T32 校园内的课程），因为参与的教师通过使用生物物理方法而团结起来。质量和 学生的数量，参与的教师与强大的培训记录，多样化和资金充足的科学 投资组合，以及培训计划的重点独特性形成了这个分子坚如磐石的基础 生物物理学培训计划提案。 !