Administrative Core

基因工程猪器官移植在狒狒身上的应用： 免疫学和功能研究 核心D：行政核心(核心领导：David K.C.Cooper) 核心摘要/摘要 这项资金申请包括3个与转基因猪肾有关的项目， 在狒狒身上进行肝脏和心脏移植。这3个项目将由4个核心支持，这些核心将 (A)提供先进的转基因猪；(B)进行所有免疫学检测；(C)进行所有 组织病理学检查，以及(D)提供行政支助。 管理核心D的主要目标是提供一个组织结构来 促进拟议项目的成功，并协调科学方法和 项目1-3与核心A、B和C之间的物流。项目之间的相互作用 而核心对于整个提案的成功至关重要。协作和 本提案参与者之间的协调将在期间得到最高优先 5年的资助期。

GENETICALLY-ENGINEERED PIG ORGAN TRANSPLANTATION IN BABOONS: IMMUNOLOGICAL AND FUNCTIONAL STUDIES CORE D: ADMINISTRATIVE CORE (Core Lead: David K.C. Cooper) CORE SUMMARY/ABSTRACT This request for funding includes 3 Projects relating to genetically-engineered pig kidney, liver, and heart transplantation in baboons. The 3 Projects will be supported by 4 Cores that will (A) provide the advanced GE pigs, (B) perform all of the immunological assays, (C) carry out all of the histopathology examinations, and (D) provide administrative support. The principal goal of Administrative Core D is to provide an organizational structure to facilitate the success of the proposed Projects, and to coordinate scientific approaches and logistics between Projects 1-3 and Cores A, B, and C. The interactions between the Projects and Cores are essential to the success of the proposal as a whole. Collaboration and coordination between the participants in this proposal will receive the highest priority during the 5-year period of funding.