Head and Neck Training Program in Surgical Oncology

外科肿瘤学头颈培训计划

• 批准号: 10429955
• 负责人: JAMES A FAGIN
• 金额: $ 15.83万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10429955
• 关键词: Head and neck structure; Surgical Oncology; Training Programs

PROJECT SUMMARY/ABSTRACT Originally awarded in 1992, this application requests a five-year renewal of the T32 Head and Neck Training Program in Surgical Oncology at Memorial Sloan Kettering Cancer Center (MSK). The mission of the Head and Neck T32 program is to train a highly selected group of talented head and neck oncologic surgeons to become high-caliber translational scientists and future academic leaders who will be positioned to advance the management of head and neck cancers. MSK, an NCI-designated comprehensive cancer center, provides a fertile environment rich in scientific and clinical resources that support intensive training in translational research. This T32's research training strategy integrates the following key components: (1) a committed and experienced Program Faculty spanning a wide range of scientific disciplines, with established track records of successful mentorship; (2) immersion into rigorous scientific research training in an R01-funded laboratory with appropriate guidance; (3) didactic research coursework; and (4) career development workshops. Each year, two new postdoctoral (MD or MD/PhD degrees) trainees are appointed to the Head and Neck T32 training grant for two contiguous years of dedicated research training. During this period, Head and Neck T32 trainees engage full-time in basic or translational mentored research related to head and neck cancers. Areas of potential research include genomics, molecular biology, cell biology, signal transduction, immunology, transgenic mouse modeling, chemoprevention, experimental therapeutics, and others. Research projects are matched to the particular academic interests and goals of the T32 trainee. Head and NeckT32 trainees will also enter a formal didactic program in head and neck oncology and research training, designed to supplement their individualized mentored research training. Career development workshops and seminars will help to prepare the T32 trainee for a successful competitive academic career. These workshops focus on grant writing skills, applying for career development awards, and developing the tools necessary for future independent research support. Head and Neck T32 trainees will be monitored closely and are expected to meet training milestones at designated time points. Specific expectations are delineated for trainee publications, grant submissions, national meeting presentations, and attendance at didactic conferences. Historically, a high proportion of trainees supported by the MSK Head and Neck T32 training program have entered academic head and neck surgical oncology and gone on to become prominent figures in the field, reflecting the effectiveness of this continuing program.

项目摘要/摘要 该申请最初于1992年颁发，要求将T32头颈部训练续期5年。 在纪念斯隆-凯特琳癌症中心(MSK)的外科肿瘤学项目。首领的使命 And Neck T32计划旨在培养一批才华横溢的头颈肿瘤外科医生，以 成为高素质的翻译科学家和未来的学术领袖，他们将定位于推动 头颈部癌症的管理。MSK是NCI指定的综合性癌症中心，提供 肥沃的环境，丰富的科学和临床资源，支持翻译强化培训 研究。S的这项T32‘科研训练战略包括以下几个关键组成部分：(1)承诺和 经验丰富的计划教员，横跨广泛的科学学科，拥有以下方面的良好记录 成功的指导；(2)在R01资助的实验室沉浸在严格的科学研究培训中， 适当的指导；(3)教学研究课程；(4)职业发展研讨会。每年， 两名新的博士后(医学博士或医学博士/博士学位)受训人员被任命参加头颈T32培训 为连续两年的专门研究培训提供资助。在此期间，头颈T32实习生 全职从事与头颈癌相关的基础或翻译指导研究。范围： 潜在的研究包括基因组学、分子生物学、细胞生物学、信号转导、免疫学、 转基因小鼠建模、化学预防、实验疗法等。研究项目有 与T32学员的特定学术兴趣和目标相匹配。Head和NeckT32实习生将 还参加了头颈部肿瘤学和研究培训的正式教学计划，旨在补充 他们的个性化指导式研究培训。职业发展讲习班和研讨会将有助于 为T32实习生为成功竞争激烈的学术生涯做好准备。这些研讨会的重点是赠款的编写。 技能，申请职业发展奖，开发未来独立所需的工具 研究支持。头部和颈部T32学员将受到密切监控，预计将接受培训 指定时间点的里程碑。具体的期望被描绘为实习生出版物，赠款 提交报告、全国会议报告和出席说教会议。从历史上看，一个高点 MSK Head and Neck T32培训计划支持的学员比例已进入学术阶段 头颈外科肿瘤学，并成为该领域的杰出人物，反映了 这一持续计划的有效性。

项目成果

Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus.

• DOI: 10.1002/hed.23877
• 发表时间: 2016-02
• 期刊: Head & neck
• 作者: Price DL;Li P;Chen CH;Wong D;Yu Z;Chen NG;Yu YA;Szalay AA;Cappello J;Fong Y;Wong RJ
• 通讯作者: Wong RJ

Surgical technique refinements in head and neck oncologic surgery.

头颈肿瘤手术的手术技术改进。

• DOI: 10.1002/jso.21454
• 发表时间: 2010
• 期刊: Journal of surgical oncology
• 影响因子: 2.5
• 作者: Liu,JeffreyC;Shah,JatinP
• 通讯作者: Shah,JatinP

An integrated simulator for endolaryngeal surgery.

• DOI: 10.1002/lary.22441
• 发表时间: 2012-01
• 期刊: LARYNGOSCOPE
• 影响因子: 2.6
• 作者: Nixon, Iain J.;Palmer, Frank L.;Ganly, Ian;Patel, Snehal G.
• 通讯作者: Patel, Snehal G.

The relationship of loss of heterozygosity to tobacco exposure and early recurrence in head and neck squamous cell carcinoma.

杂合性丧失与烟草暴露和头颈鳞状细胞癌早期复发的关系。

• DOI: 10.1016/s0002-9610(05)80094-7
• 发表时间: 1994
• 期刊: American journal of surgery
• 影响因子: 3
• 作者: Lydiatt,WM;Davidson,BJ;Shah,J;Schantz,SP;Chaganti,RS
• 通讯作者: Chaganti,RS

Oncolytic herpesvirus effectively treats murine squamous cell carcinoma and spreads by natural lymphatics to treat sites of lymphatic metastases.

• DOI: 10.1089/104303402320138998
• 发表时间: 2002-07
• 期刊: Human gene therapy
• 影响因子: 4.2
• 作者: R. Wong;J. Joe;Se-Heon Kim;J. Shah;B. Horsburgh;Y. Fong