Rapid Point of Care Test to Quantify HIV Drugs for Adherence Monitoring

目标是开发新型、低成本、实时床旁（POC）检测方法，用于抗逆转录病毒药物依从性监测： - 衡量抗逆转录病毒药物长期（> 7天）依从性的快速护理点方法 - 能够测量各种生物基质中的药物水平，例如，尿液、毛发、干血斑等。 - 能够监测PrEP依从性、ART依从性以触发依从性干预措施、与长效ART或PrEP相关的长尾以及PrEP或ART药物水平的献血（作为HIV暴露或感染的风险指标）

The goal is to develop novel, low-cost, real-time point-of-care (POC) assays for antiretroviral drug adherence monitoring: - Rapid point-of-care methods that measure long-term (> 7 days) adherence to antiretroviral drugs - Ability to measure drug levels in various biological matrices, e.g., urine, hair, dried blood spots, etc. - Ability to monitor PrEP adherence, ART adherence to trigger adherence interventions, the long-tail associated with long-acting ART or PrEP, and blood donations for PrEP or ART drug levels (as a risk indicator of HIV exposure or infection)