Improving the reproducibility of manufacturing a polymer-based electrochemical sensor

提高聚合物电化学传感器制造的再现性

• 批准号: 10073816
• 金额: $ 3.38万
• 依托单位: KALIUM HEALTH LTD
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10073816
• 关键词: Improving; reproducibility; manufacturing; polymer; based

Chronic kidney disease affects 800 million people worldwide, and is complex and costly to manage. A major clinical problem in kidney disease is that potassium levels rise, which can be fatal. Currently there is no alternative to a hospital- or clinic-based blood draw to measure potassium. However, new treatments and payment models are driving a growing wave of innovation. Our digital blood potassium monitoring solution will avoid costly hospital admissions and help patients lead a better lifestyle.Kalium Health has identified opportunities for products that will open up new markets in personalised healthcare, based on our blood sensing technology. In this project we will optimise our manufacturing processes and quality control methodologies to enable high-volume manufacturing of our sensors.To achieve this, we will collaborate with the National Physical Laboratory who will develop custom methods and instrumentation to perform analytical characterisation of the structural, physical and chemical properties of our sensors, to give us insights into how these impact reproducibility and stability. Successful completion of the project will result in optimised manufacturing processes and improved quality controls, enabling us to advance through regulatory approval and market launch.

慢性肾脏疾病影响全球8亿人，并且管理复杂且成本高昂。肾脏疾病的一个主要临床问题是钾水平升高，这可能是致命的。目前，没有替代医院或诊所抽血来测量钾。然而，新的治疗和支付模式正在推动越来越多的创新浪潮。我们的数字化血钾监测解决方案将避免昂贵的住院费用，并帮助患者过上更好的生活方式。基于我们的血液传感技术，Kalium Health已经确定了产品的机会，这些产品将在个性化医疗保健领域开辟新市场。在该项目中，我们将优化我们的制造工艺和质量控制方法，以实现传感器的大批量生产。为此，我们将与国家物理实验室合作，后者将开发定制方法和仪器，对我们的传感器的结构，物理和化学特性进行分析表征，让我们深入了解这些特性如何影响重现性和稳定性。该项目的成功完成将优化制造工艺和改善质量控制，使我们能够通过监管批准和市场推出。