Development of a smartphone-based device to detect fluid overload among postpartum women with hypertensive disorders of pregnancy

开发基于智能手机的设备来检测患有妊娠期高血压疾病的产后妇女的液体超负荷

基本信息

  • 批准号:
    10437610
  • 负责人:
  • 金额:
    $ 15.15万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-07-01 至 2024-03-31
  • 项目状态:
    已结题

项目摘要

PROJECT ABSTRACT Hypertensive disorders of pregnancy contribute to a significant proportion of maternal morbidity and mortality and are the most common reason for hospital readmission postpartum. While treatment of hypertension is the cornerstone of postpartum management, emerging evidence suggests that implementation of robust remote blood pressure monitoring and treatment programs alone do not reduce maternal morbidity or hospital readmissions related to postpartum fluid overload and heart failure symptoms. The ability to predict which women will develop these complications and pursue more aggressive treatment with diuresis prior to hospital discharge or in the first week postpartum is limited. The overall goal of this line of research is to develop and implement a convenient congestion prediction device for home use in conjunction with home blood pressure monitoring in a postpartum population following a hypertensive disorder of pregnancy. In this application, the objective is to develop and test a smartphone-based device to predict fluid overload in patients with preeclampsia through three specific aims: 1) to build multiple smartphone-based devices to assess volume status via a congestion prediction index in postpartum women with preeclampsia, 2) to collect patient training data with the devices, optimize their accuracy in assessing volume status, and identify and create the final real-time device and 3) to validate the final device prospectively in response to known fluid changes among a new cohort of postpartum women with preeclampsia. The research proposed in this application is innovative in its novel adaptation of evidence-based approaches to fluid assessment in heart failure patients to an understudied postpartum population with significant morbidity, its use of a smartphone form factor and the design and the proposed testing of multiple devices to optimize effectiveness and convenience. This proposal is significant as it will provide an opportunity to develop and assess the feasibility of smartphone- based assessment of fluid status among postpartum women with preeclampsia. Effective interventions to improve postpartum hypertension care coupled with innovative remote strategies have broad implications for improving maternal morbidity and reducing disparities in care. Our findings will provide a valuable framework to inform a future randomized trial of remote assessment and management of fluid status in the postpartum period. Successful completion of this line of research would represent a transformation in postpartum management of women with preeclampsia and have a direct impact to improve hypertension and cardiovascular-related maternal morbidity and mortality.
项目摘要

项目成果

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Alisse Hauspurg其他文献

Alisse Hauspurg的其他文献

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{{ truncateString('Alisse Hauspurg', 18)}}的其他基金

Postpartum low-dose aspirin to augment vascular recovery following a hypertensive disorder of pregnancy
产后小剂量阿司匹林可促进妊娠高血压疾病后的血管恢复
  • 批准号:
    10644089
  • 财政年份:
    2023
  • 资助金额:
    $ 15.15万
  • 项目类别:
Development of a smartphone-based device to detect fluid overload among postpartum women with hypertensive disorders of pregnancy
开发基于智能手机的设备来检测患有妊娠期高血压疾病的产后妇女的液体超负荷
  • 批准号:
    10196326
  • 财政年份:
    2021
  • 资助金额:
    $ 15.15万
  • 项目类别:
Development of a smartphone-based device to detect fluid overload among postpartum women with hypertensive disorders of pregnancy
开发基于智能手机的设备来检测患有妊娠期高血压疾病的产后妇女的液体超负荷
  • 批准号:
    10622547
  • 财政年份:
    2021
  • 资助金额:
    $ 15.15万
  • 项目类别:

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