The BLOODSAFE Data Coordinating Center: A Data Center for More SafeTransfusions in Sub-Saharan Africa

项目摘要 该项目的目标是提供生物统计领导地位和数据管理基础设施 BLOODSAFE倡议，这是一项NHLBI倡议，旨在增加可用于 撒哈拉以南非洲的输血。这种领导包括协调多个项目的活动， 与NHLBI的科学家就项目监督和提供有关以下各方面的专业知识进行合作 研究设计与实施。这种专门知识包括但不限于与当地专家的协调， 向当地专家提供培训，协助研究设计，协调数据要素 多项研究，协助实施干预措施，数据管理，数据质量保证， 数据分析和研究成果传播，以确保将发现传达给科学 并及时将其转化为当地最佳做法。这些目标将通过以下方式实现 完成以下目标：在所有研究中提供研究协调活动和监督 研究发展阶段，包括监管监督、后勤支助和培训机会 与NHLBI合作；在研究设计、启动和实施方面提供专业知识；在以下方面提供专业知识 数据管理包括数据元素的标准化、数据采集仪器的设计、 开发数据质量保证系统和样本跟踪系统；并在以下方面提供专门知识 研究报告、数据分析和结果传播的所有方面，以及开发新的分析 为实现研究目标所需的战略。

Project Summary The goal of this project is to provide biostatistical leadership and data management infrastructure for the BLOODSAFE initiative, an NHLBI initiative which seeks to increase the supply of safe blood available for transfusion in Sub-Saharan Africa. This leadership includes coordination of activities across multiple projects, collaboration with scientists at NHLBI on program oversight and provision of expertise regarding all aspects of study design and implementation. This expertise includes but is not limited to coordination with local experts, provision of training to local experts, assistance with study design, harmonization of data elements across multiple studies, assistance with implementation of interventions, data management, data quality assurance, data analysis and study finding dissemination to ensure that discoveries are communicated to the scientific community and translated into local best practices in a timely manner. These goals will be fulfilled by completion of the following aims: provide study coordination activities and oversight across all studies at all stages of study development, including regulatory oversight, logistical support and training opportunities in conjunction with NHLBI; provide expertise in study design, initiation and implementation; provide expertise in data management including standardization of data elements, design of data collection instruments, development of data quality assurance systems and systems for specimen tracking; and provide expertise in all aspects of study reporting, data analysis and result dissemination and development of novel analysis strategies as required for fulfilment of study objectives.