Administrative Core

摘要 行政核心(核心A)将由耶鲁大学首席研究员芭芭拉·伯蒂斯博士指导 《肺癌中的头颈孢子》(yhn-sporate)，由Edward Kaftan博士联合执导， 方案财务管理团队和协理署长Michele Dingus。Erica Golemis博士和 温德尔·雅布罗将担任福克斯·蔡斯癌症中心和北卡罗来纳大学的现场负责人， 分别进行了分析。行政核心的仔细监督将是确保YHN成功的关键-- 孢子。行政核心将作为所有青年调查人员的中心协调点， 负责战略和科学指导，并监测所有项目和核心的进展情况 孢子的翻译目标。核心董事和联席董事将负责领导 孢子，设定翻译研究的优先事项，确定新的翻译研究机会，监测 所有项目、核心和发展项目的进展情况，并确定项目方向的变化， 根据需要进行核心和翻译研究。YHN孢子调查人员之间的互动将通过以下方式促进 核心A通过理性和严谨的方式加快实验室结果到床边的转化 翻译和临床研究。如果需要，核心A主管将管理孢子之间的冲突 调查人员。作为一个团队，核心人员将提供财务监督，保持沟通 项目和核心领导人并协调每两周举行一次的会议、执行委员会的季度会议、 内部/外部咨询委员会的年度会议和一年一度的YSHN孢子务虚会。除了……之外 这些功能，核心将是NCI的主要接口，福克斯·蔡斯癌症中心，华盛顿大学 北卡罗来纳州、头颈部或其他以疾病或途径为重点的孢子，耶鲁大学癌症中心和耶鲁大学 医学院，并将协调外联工作，包括出版物(内部和外部)，网站 发展、研讨会和患者/研究倡导活动。通过这些管理活动，Core A将是组织yhn-sporate计划的关键，对于推动科学战胜治疗是必不可少的。 头颈部癌症的耐药性，开发模型和方法来推动该领域的发展，并指导 新一代头颈癌翻译研究人员。

SUMMARY The Administrative Core (Core A) will be directed by Dr. Barbara Burtness, Principal Investigator of the Yale Head and Neck SPORE in Lung Cancer (YHN-SPORE), and co-directed by Dr. Edward Kaftan with support from the program financial management team and Michele Dingus, Associate Administrator. Drs. Erica Golemis and Wendell Yarbrough will serve as Site Leaders for Fox Chase Cancer Center and University of North Carolina, respectively. Careful oversight by the Administrative Core will be critical to ensure the success of the YHN- SPORE. The Administrative Core will serve as the central coordination point for all YHN-SPORE investigators, with responsibility for strategic and scientific direction, and monitoring progress of all projects and cores towards the translational goals of the SPORE. The Core Director and Co-Directors will have responsibility for leading the SPORE, setting translational research priorities, identifying new translational research opportunities, monitoring the progress of all projects, cores and developmental projects and determining changes in direction of projects, cores and translational research as needed. Interactions among YHN-SPORE investigators will be facilitated by Core A to accelerate the translation of laboratory findings to the bedside through rational and rigorous translational and clinical studies. If required, the Core A Director will manage conflicts among SPORE investigators. As a team, the Core personnel will provide financial oversight, maintain communication among project and core leaders and coordinate bi-weekly meetings, quarterly meetings of the Executive Committee, annual meetings of the Internal/External Advisory boards and an annual YSHN-SPORE retreat. In addition to these functions, the Core will be the primary interface with the NCI, Fox Chase Cancer Center, University of North Carolina, head and neck or other disease- or pathway-focused SPOREs, Yale Cancer Center and Yale School of Medicine, and will coordinate outreach efforts, including publications (internal and external), website development, seminars, and patient/research advocacy activities. Through these administrative activities, Core A will be essential to the organization of the YHN-SPORE program, to advancing science to overcome treatment resistance in head and neck cancer, developing models and approaches to advance the field, and mentoring a new generation of head and neck cancer translational researchers.