Administrative Core

总结 管理核心（核心A）将由耶鲁大学首席研究员Barbara Burtness博士指导。 头颈部肺癌孢子（YHN-SPORE），由Edward Kaftan博士共同指导， 该计划的财务管理团队和米歇尔丁格斯，副署长。埃里卡戈莱米斯博士和 温德尔雅布罗将担任福克斯大通癌症中心和北卡罗来纳州大学的现场负责人， 分别行政核心的仔细监督对于确保YHN的成功至关重要- 孢子。行政核心将作为所有YHN-SPORE调查人员的中心协调点， 负责战略和科学方向，并监测所有项目和核心的进展， SPORE的翻译目标。核心主任和联席主任将负责领导 SPORE，确定转化研究的优先事项，确定新的转化研究机会，监控 所有项目、核心项目和发展项目的进展情况，并确定项目方向的变化， 根据需要进行核心和转化研究。YHN-SPORE调查人员之间的互动将通过以下方式促进： 核心A，通过合理和严格的检查， 转化和临床研究。如果需要，核心A控制器将管理SPORE investigators.作为一个团队，核心人员将提供财务监督， 项目和核心领导人，并协调执行委员会的双周会议，季度会议， 内部/外部咨询委员会的年度会议和年度YSHN-SPORE务虚会。除了 这些功能，核心将是与国家癌症研究所，福克斯蔡斯癌症中心，大学的主要接口。 北卡罗来纳州，头颈部或其他疾病或途径为重点的SPORE，耶鲁大学癌症中心和耶鲁大学 将协调外联工作，包括出版物（内部和外部）、网站 发展、研讨会和患者/研究宣传活动。通过这些行政活动， A将是必不可少的组织YHN孢子计划，以推进科学，克服治疗 头颈癌的耐药性，开发模型和方法来推进该领域，并指导 新一代头颈癌转化研究人员。

SUMMARY The Administrative Core (Core A) will be directed by Dr. Barbara Burtness, Principal Investigator of the Yale Head and Neck SPORE in Lung Cancer (YHN-SPORE), and co-directed by Dr. Edward Kaftan with support from the program financial management team and Michele Dingus, Associate Administrator. Drs. Erica Golemis and Wendell Yarbrough will serve as Site Leaders for Fox Chase Cancer Center and University of North Carolina, respectively. Careful oversight by the Administrative Core will be critical to ensure the success of the YHN- SPORE. The Administrative Core will serve as the central coordination point for all YHN-SPORE investigators, with responsibility for strategic and scientific direction, and monitoring progress of all projects and cores towards the translational goals of the SPORE. The Core Director and Co-Directors will have responsibility for leading the SPORE, setting translational research priorities, identifying new translational research opportunities, monitoring the progress of all projects, cores and developmental projects and determining changes in direction of projects, cores and translational research as needed. Interactions among YHN-SPORE investigators will be facilitated by Core A to accelerate the translation of laboratory findings to the bedside through rational and rigorous translational and clinical studies. If required, the Core A Director will manage conflicts among SPORE investigators. As a team, the Core personnel will provide financial oversight, maintain communication among project and core leaders and coordinate bi-weekly meetings, quarterly meetings of the Executive Committee, annual meetings of the Internal/External Advisory boards and an annual YSHN-SPORE retreat. In addition to these functions, the Core will be the primary interface with the NCI, Fox Chase Cancer Center, University of North Carolina, head and neck or other disease- or pathway-focused SPOREs, Yale Cancer Center and Yale School of Medicine, and will coordinate outreach efforts, including publications (internal and external), website development, seminars, and patient/research advocacy activities. Through these administrative activities, Core A will be essential to the organization of the YHN-SPORE program, to advancing science to overcome treatment resistance in head and neck cancer, developing models and approaches to advance the field, and mentoring a new generation of head and neck cancer translational researchers.