Proof of Principle Clinical Study to Evaluate a Novel Medical Device for Orthostatic Hypotension

直立性低血压（OH）是一种非常常见且使人虚弱的疾病，由站立时血压下降引起。它会引起头晕、跌倒和昏厥等症状。它影响了多达五分之一的老年人，降低了他们的生活质量，增加了他们住院和痴呆的风险。关于如何最好地治疗这种疾病的研究很少，但由于这种疾病的性质，药物并不是最好的选择。OH患者以前报告说，他们更喜欢非药物治疗，但这些治疗的依从性较差（例如，喝大量的水）。在站立时激活肌肉是一种潜在的治疗方法，lsotech有限公司发明了一种设备，该公司专门从事发明和开发医疗设备以提高生活质量。他们的新设备可以作为腕表佩戴，当患者激活时，会引起肌肉收缩，暂时升高血压，这有助于缓解站立时的症状，防止跌倒和受伤。这种设备将极大地改善这种疾病的治疗方式，并可以帮助大量老年人。

Orthostatic hypotension (OH) is a very common and debilitating condition, caused by a drop in blood pressure (BP) on standing up. It can cause symptoms such as dizziness, falls and fainting. It affects up to one in five older people, reduces their quality of life and increases their risk of hospitalisation and dementia.There has been very little research on how best to treat this condition but, due to the nature of the condition, medications are not the best option. People with OH have previously reported that they prefer non-drug treatments, but these have poor adherence (e.g. drinking large volumes of water). Activating the muscles during standing is one potential treatment and a device has been invented by the company lsotech Ltd, who specialise in inventing and developing medical devices to improve quality of life. Their new device is worn as a wristwatch which when activated by the patient, causes contraction of muscles which temporarily increases BP, which should help relieve symptoms on standing up and prevent falls and injuries.This device would dramatically improve the way this condition is managed and could help huge numbers of older people.