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Proof of Principle Clinical Study to Evaluate a Novel Medical Device for Orthostatic Hypotension

Proof of Principle Clinical Study to Evaluate a Novel Medical Device for Orthostatic Hypotension
评估新型直立性低血压医疗器械的原理临床研究证明
批准号:
10076358
负责人:
金额:
$6.17万
依托单位:
依托单位国家:
英国
项目类别:
Grant for R&D
财政年份:
2023
资助国家:
英国
项目状态:
已结题
起止时间:
2023 至 --

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中文摘要
翻译
直立性低血压(OH)是一种非常常见且使人衰弱的疾病,由站立时血压(BP)下降引起。它会引起头晕、福尔斯和昏厥等症状。它影响多达五分之一的老年人,降低他们的生活质量,增加他们住院和痴呆症的风险。关于如何最好地治疗这种疾病的研究很少,但由于这种疾病的性质,药物不是最佳选择。OH患者以前曾报告他们更喜欢非药物治疗,但这些治疗的依从性很差(例如饮用大量水)。在站立时激活肌肉是一种潜在的治疗方法,专门从事发明和开发医疗设备以提高生活质量的lsotech有限公司发明了一种设备。他们的新设备是作为手表佩戴的,当病人激活时,会引起肌肉收缩,暂时增加血压,这应该有助于缓解站立时的症状,防止福尔斯和受伤。这种设备将大大改善这种情况的管理方式,并可以帮助大量的老年人。
英文摘要
Orthostatic hypotension (OH) is a very common and debilitating condition, caused by a drop in blood pressure (BP) on standing up. It can cause symptoms such as dizziness, falls and fainting. It affects up to one in five older people, reduces their quality of life and increases their risk of hospitalisation and dementia.There has been very little research on how best to treat this condition but, due to the nature of the condition, medications are not the best option. People with OH have previously reported that they prefer non-drug treatments, but these have poor adherence (e.g. drinking large volumes of water). Activating the muscles during standing is one potential treatment and a device has been invented by the company lsotech Ltd, who specialise in inventing and developing medical devices to improve quality of life. Their new device is worn as a wristwatch which when activated by the patient, causes contraction of muscles which temporarily increases BP, which should help relieve symptoms on standing up and prevent falls and injuries.This device would dramatically improve the way this condition is managed and could help huge numbers of older people.
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