Core A: Administrative

核心A：摘要 核心A将负责提供行政和生物统计支助， 程序项目。核心将与NIAID的计划管理层以及 外部科学咨询小组、协调会议和进度报告。预算报告 向NIH和FDA提交的年度报告将由核心A协调。它还将有助于 整合研究者、他们的实验发现和他们的想法， 临床和临床努力，以集中努力提高临床结果。行政 将采用一种结构来完成这些职能，在这种结构中，核心领导人莱利博士被建议 由项目执行委员会和核心领导人组成，科学顾问提供投入 以马克思U19的财务和会议后勤将由Chelsey女士组织。 Molineaux将每月与U19 PI以及每个项目和核心领导人会面。肖医生 将为科学项目和核心项目以及 临床试验的设计和实施。因此，具体目标是： SA1：协调科学家、私营部门合作伙伴和NIH之间的互动 有效实施拟议计划和项目的人员。 SA 2：监督所有预算事项，包括监测每月开支， 准备非竞争性续约申请。 SA3：为项目提供统计支持，特别是项目4中拟定的临床试验

CORE A: ABSTRACT Core A will be responsible for providing administrative and biostatistics support for the overall program project. The Core will interact with Program management at NIAID and with the external Scientific Advisory Panel, coordinating meetings and progress reports. Budget reports and annual reports to NIH and FDA will be coordinated by Core A. It will also serve to amalgamate the investigators, their experimental findings and their ideas, evaluation of pre- clinical and clinical efforts to focus efforts on enhancing the clinical outcome. The administrative functions will be accomplished using a structure in which the Core Leader, Dr. Riley, is advised by an Executive Committee of Project and Core Leaders with input from the Scientific Advisory Committee. The finances and meeting logistics of the U19 will be organized by Ms. Chelsey Molineaux who will meet monthly with the U19 PI and each Project and Core Leader. Dr. Shaw will provide comprehensive biostatistics support for the scientific project and core, and for the design and implementation of the clinical trial. Therefore, the specific aims are: SA1: To coordinate the interactions among scientists, private sector partners, and NIH personnel regarding efficient implementation of proposed plans and projects. SA2: To oversee all budgetary matters, including monitoring of monthly expenses and preparation of non-competitive renewal applications. SA3: To provide statistical support for projects, especially the proposed clinical trial in Project 4