Improving the HIV Care Cascade in Kenya through Implementation Science Training

摘要 本申请旨在更新题为“改善艾滋病毒护理”的D43艾滋病毒研究培训补助金 通过实施科学培训在肯尼亚建立级联”， 与肯尼亚机构的合作以及我们前4年的成功培训。2013年9月至 目前，该计划的重点是增加肯雅塔国家医院（KNH）的能力， 肯尼亚的教学和转诊医院，以及卫生部（MOH），在实施科学研究 针对艾滋病毒检测、与护理的联系、抗逆转录病毒启动和病毒抑制，这是一个连续体，被称为 艾滋病毒护理级联。在此期间，10名KNH Care Cascade（KNHCC）学员获得了MPH或PhD学位 学位，并为KNH及其在卫生部和内罗毕大学（UON）的合作伙伴奠定了坚实的基础， 为建立一个执行科学和传播研究中心迈出了大胆的一步， 卓越此更新申请将为培训，教学和研究提供关键支持 实现这一愿景所需的活动。该计划将继续由Carey Farquhar博士领导， 华盛顿大学国际艾滋病研究和培训计划（IARTP）自2003年以来，和博士约翰Kinuthia，负责人 KNH研究和项目部的一名研究员。将提供两个互补的培训轨道：1） MPH/博士三明治计划在实施科学，将发生在西雅图，美国（第一年）和 内罗毕，肯尼亚（2-4年）和2）一个为期一年的证书课程，其中将包括1个月的指导和 在华盛顿大学的相关课程，然后在KNH完成额外的面对面课程和研讨会 和UON，UW电子学习课程，并完成一个指导研究项目。培训候选人 将在KNH或MOH拥有永久职位，可能来自医学，护理，药房或公共卫生。 我们还将提供为期3天至1周的短期国内培训，以接触更多的KNH 卫生部专业人员。短期培训将建立更广泛的机构能力，促进 了解关键的研究概念和实践，并确定未来学位的最佳候选人， 证书培训。一个指导委员会，由来自世界各地的主要研究人员、教育工作者和决策者组成， 所有4个机构（华盛顿大学、新罕布什尔大学、安大略大学、卫生部）都将与KNHCC项目主任和联合主任密切合作 并定期接受外部培训咨询小组（TAG）的意见，以确保每位学员的成功 和整个计划。这一成功将转化为改善肯尼亚的艾滋病毒护理级联， 通过开展高质量和与当地相关的研究，影响国家指导方针和政策， 培训下一代非洲执行科学研究人员。

ABSTRACT This application seeks to renew the D43 HIV Research Training grant entitled, “Improving the HIV Care Cascade in Kenya through Implementation Science Training,” by building on longstanding UW collaborations with Kenyan institutions and our first 4 years of successful training. From September 2013 to the present, the program has focused on increasing capacity at Kenyatta National Hospital (KNH), the largest teaching and referral hospital in Kenya, and the Ministry of Health (MOH), in implementation science research targeting HIV testing, linkage to care, antiretroviral initiation and viral suppression, a continuum known as the HIV care cascade. During this period, 10 KNH Care Cascade (KNHCC) trainees have earned MPH or PhD degrees and laid a solid foundation for KNH and its partners at MOH and University of Nairobi (UON) to take a bold step towards creation of an Implementation Science and Dissemination Research Center of Excellence. This renewal application will provide critical support for the training, teaching and research activities needed to realize this vision. The program will continue to be led by Dr. Carey Farquhar, Director of the UW International AIDS Research and Training Program (IARTP) since 2003, and Dr. John Kinuthia, Head of the Department of Research and Programs at KNH. Two complementary training tracks will be offered: 1) MPH/PhD sandwich program in implementation science which will take place in Seattle, USA (year 1) and in Nairobi, Kenya (years 2-4) and 2) a 1-year certificate program which will include 1 month of mentoring and relevant coursework at the UW followed by completion of additional in-person courses and workshops at KNH and UON, UW e-learning courses, and completion of a mentored research project. Candidates for the training will have permanent positions at KNH or MOH, and may be from medicine, nursing, pharmacy or public health. We will also offer shorter in-country trainings lasting from 3 days to 1 week that reach a larger number of KNH and MOH professional staff. The short-term trainings will build broader institutional capacity, promote awareness of key research concepts and practices, and identify the best candidates for future degree and certificate training. A Steering Committee comprised of leading researchers, educators and policy makers from all 4 institutions (UW, KNH, UON, MOH) will work closely with the KNHCC Program Director and Co-director and receive regular input from an external Training Advisory Group (TAG) to ensure success of each trainee and the overall program. This success will translate into improving the HIV care cascade in Kenya and the region by producing high-quality and locally relevant research, influencing national guidelines and policies, and training the next generation of African researchers in implementation science.