Core B -Developmental Core

核心B：项目摘要/摘要：加州大学洛杉矶分校-CDU CFAR发展核心包括整个 CFAR计划，为其关键目标提供后勤和财政支持。此核心的主要重点领域包括 培养下一代艾滋病研究人员，激发艾滋病研究创新，培育 协作的跨学科伙伴关系，并利用CFAR资源。 这些领域在这个核心的保护伞下是交错和协同的，并结合在一起以增强 CFAR作为协调、激励和推动开创性工作的机制的总体目标 与结束艾滋病大流行有关的研究。邀请和留住具有新想法的新研究人员至关重要 为了推动研究朝着有希望的新方向发展，然而对早期职业调查人员的资助仍然持平，并已 近年来，职业生涯中期的调查人员遭到了拒绝。提供指导和资金支持将是一个关键目标 投资于CFAR合作伙伴的未来：加州大学洛杉矶分校、CDU、港湾-加州大学洛杉矶分校和大洛杉矶 弗吉尼亚州洛杉矶。此外，由于传统的孤立研究模式正在让位于多学科研究 从多个角度解决棘手研究问题的合作，这一核心将把 跨学科和机构的研究人员，并鼓励艾滋病研究之外的研究人员加入 与CFAR研究人员的力量。 这些多管齐下的活动的总和将产生： ·艾滋病研究的背景、职业阶段和领域不同的研究人员群体 ·这些研究人员的互动和合作，包括导师关系 ·吸引外部领域专家参与艾滋病研究的环境 ·不断发展的新研究想法组合，旨在产生NIH资助的开创性项目 这一核心将通过多管齐下的方法实现这些目标。这将包括程序性和 与辅导和职业发展有关的授课活动(目标1)，支持征聘新的调查员 加州大学洛杉矶分校和CDU(AIM 2)，管理创新研究项目种子试验资助计划(AIM 3)，并利用慈善和国家资金加强这些活动(目标4)。这些目标和目标 它们支持彼此重叠，并与整个CFAR计划重叠。

Core B: Project Summary/Abstract: The UCLA-CDU CFAR Developmental Core encompasses the entire CFAR program, providing logistical and financial support for its key goals. Key focus areas for this Core include cultivating the next generation of AIDS researchers, sparking innovation in AIDS research, and cultivating collaborative trans-disciplinary partnerships, and leveraging CFAR resources. These areas are interdigitated and synergistic under the umbrella of this Core and combine to augment the overarching purpose of the CFAR as a mechanism to coordinate, motivate, and enable ground-breaking research relevant to ending the AIDS pandemic. Inviting and retaining new researchers with new ideas is critical to move research in promising new directions, yet funding for early career investigators remains flat and has declined for mid-career investigators in recent years. Providing mentoring and funding support will be a key goal of this Core, investing in the future of the CFAR partners: UCLA, CDU, Harbor-UCLA, and the Greater Los Angeles VA. Moreover, because traditional models of siloed research are giving way to multi-disciplinary collaborations that attack difficult research questions from multiple angles, this Core will bring together investigators across disciplines and institutions, and encourage investigators outside AIDS research to join forces with CFAR researchers. The sum of these multi-pronged activities will be to generate: • A diverse group of researchers in terms of backgrounds, career stages, and areas of AIDS research • Interactions and collaborations of these researchers, including mentorship relationships • An environment that draws experts in outside fields into AIDS research • An evolving portfolio of new research ideas that is cultivated to yield groundbreaking NIH-funded projects This Core will accomplish these goals through a multi-pronged approach. This will include programmatic and didactic activities related to mentorship and career development (Aim 1), support for recruiting new investigators to UCLA and CDU (Aim 2), administering a pilot funding program for seeding innovative research projects (Aim 3), and leveraging philanthropic and state funds to augment these activities (Aim 4). These aims and the goals they support overlap with each other and with the entire CFAR program.