ERC Einstein Rockefeller CUNY Center for AIDS Research

项目总结 ERC-CFAR：发展核心 爱因斯坦-洛克菲勒-纽约大学CFAR(ERC-CFAR)发展核心将努力提供广泛的 支持培养和推进未来艾滋病毒/艾滋病研究人员的艾滋病毒/艾滋病研究事业。我们的 本次续订申请的协调策略将通过以下三个具体目标来实施 围绕着早期调查人员(Esis)。在目标1中，我们将采用多方面的指导过程， 将为每个ESI制定的单独定制的指导计划与多个论坛相结合，使ESI能够 向ERC-CFAR社区介绍他们的艾滋病毒/艾滋病研究进展，以获得反馈并开发新的 合作。在目标2中，我们将为教育信息系统提供竞争机会，参加经同行评审的环境资源中心-财务报告评审。 催化试点赠款和小额赠款计划或NIH CFAR行政补充机会。目标3 包括加强机构间和机构内合作以及科学交流的双重目标。 将通过以下方式加强合作：(I)招募非艾滋病研究人员与CFAR调查人员合作 并消除取得成功的障碍--提供高达1万美元的小额赠款和接触艾滋病毒人群； (2)组织两年一次的虚拟K-俱乐部，爱因斯坦、洛克菲勒和纽约市立大学的Esis参加， 包括由成功的EIS和ERC-CFAR开发和运营核心所作的介绍 领导了解所有可用的CFAR服务，以帮助EIS进行他们的研究项目和计划拨款 提交材料；和(3)组织一年两次的全纽约市研究专题讨论会，纽约市所有艾滋病毒/艾滋病人都参加 研究人员将从纽约不同的主要机构中挑选个人来展示他们的研究成果 前沿研究。我们将通过(I)双周刊加强ERC-CFAR调查人员之间的科学交流 跨机构ERC-CFAR虚拟研究研讨会和双周临床艾滋病中心/ERC-CFAR Grand 巡回会议；(2)ERC-CFAR特邀发言人研讨会；(3)每月举行的病毒中心会议，由13名爱因斯坦组成 病毒学家，包括9名专注于艾滋病毒、单纯疱疹病毒或丙型肝炎病毒研究的教职员工。这提供了 为所有ERC-CFAR提供一个特别的一站式商店，以了解爱因斯坦正在进行的最新病毒学研究。 ERC-CFAR的这些高度协调和积极主动的指导服务产生了令人印象深刻的影响 过去4年资助的发展核心体现在我们指导的EIS取得的成就上 其中包括2050万美元的外部赠款和250份出版物。ERC-CFAR的高度影响 发展核心的催化试点赠款计划，迄今已向EIS授予14笔试点赠款(0.46 100万美元)，反映在他们已经获得了高达8.1美元的资金 美国国立卫生研究院拨款100万美元(投资回报17.6英镑)，发表了70多篇论文。

PROJECT SUMMARY ERC-CFAR: DEVELOPMENTAL CORE The Einstein-Rockefeller-CUNY CFAR (ERC-CFAR) Developmental Core will strive to provide wide-ranging support to nurture and advance the HIV/AIDS research careers of tomorrow’s HIV/AIDS researchers. Our coordinated strategy for this renewal application will be implemented via three specific aims that are centered around early stage investigators (ESIs). In Aim 1, we will employ a multi-faceted mentoring process, which combines individually tailored mentoring plans developed for each ESI and multiple forums to enable ESIs to present their HIV/AIDS research progress to the ERC-CFAR community to garner feedback and develop new collaborations. In Aim 2, we will provide ESIs with opportunities to compete in the peer-reviewed ERC-CFAR catalytic pilot grants and microgrants programs or NIH CFAR administrative supplements opportunities. Aim 3 includes dual goals of enhancing trans- and intra-institutional collaborations and scientific communication. Collaborations will be increased by: (i) recruiting non-AIDS researchers to collaborate with CFAR investigators and by removing obstacles to succeed – both by providing microgrants up to $10K and access to HIV cohorts; (ii) organizing bi-annual virtual K-clubs that are attended by ESIs from Einstein, Rockefeller and CUNY and that include both presentations by successful ESIs and by the ERC-CFAR Developmental and Operational Core leaders about all available CFAR services that can assist ESIs in their research projects and planned grant submissions; and (iii) organizing bi-annual New York City-wide research symposia attended by all NYC HIV/AIDS researchers where individuals from the different major NYC institutions will be selected to present their cutting edge research. We will enhance scientific communication among the investigators of ERC-CFAR via (i) bi-weekly Trans-institutional ERC-CFAR virtual research seminars and biweekly Clinical AIDS Center/ERC-CFAR Grand Rounds; (ii) ERC-CFAR Invited Speaker Seminars; (iii) Monthly Virus Hub meetings consisting of 13 Einstein virologists, which includes 9 faculty members that are focused on research on HIV, HSV or HCV. This provides a special one-stop-shop for all ERC-CFAR ESIs to learn about the latest virological research going on at Einstein. The impressive impact of these highly coordinated and proactive mentoring services by the ERC-CFAR Developmental Core over the past 4 years of funding is demonstrated by accomplishments of our mentored ESIs that include $20.5 million of external grants and 250 publications. The high impact of the ERC-CFAR Developmental Core’s catalytic pilot grant program, which has awarded 14 pilot grants to ESIs so far (0.46 million) from all three participant institutions, is reflected in the fact that they have already garnered up to ~$8.1 million in NIH grants (a return on investment of 17.6) and that they have published over 70 papers.