Vaccine Response and Immunotherapeutics SWG

疫苗反应和免疫治疗(VRI)科学工作组被增加到 CFAR将于2021年促进与疫苗和其他免疫疗法相关的研究 艾滋病毒携带者(PLWH)SARS-CoV-2大流行显示出巨大的 接种疫苗对公共卫生的影响。随着科学界的许多人转向研究 艾滋病研究人员称，SARS-CoV-2和疫苗研发以前所未有的速度进行 JHU认识到将PLWH纳入疫苗研究的重要性，以及 新冠肺炎疫苗学对其他疫苗的潜在影响，包括艾滋病毒预防和 治疗性疫苗。HIV对免疫抑制的效果和后果 疫苗保护的持久性没有很好的特点，这是一个重要的研究领域。在……里面 除了冠状病毒疫苗，评估耐受性和细胞免疫的临床研究 对儿童和其他成人疫苗的反应是确定当前疫苗是否 时间表和建议适用于PLWH。这个SWG将专注于艾滋病毒和 PLWH的非HIV疫苗和免疫疗法促进疫苗科学教育， 培养初中级教师对疫苗和免疫疗法的研究兴趣， 并与其他SWG协调以实现这些目标。

The Vaccine Response and Immunotherapeutics (VRI) Scientific Working Group was added to the CFAR in 2021 to foster research related to vaccines and other immunotherapeutics for people living with HIV (PLWH). The SARS-CoV-2 pandemic has demonstrated the enormous public health impact of vaccination. As much of the scientific community pivoted to studying SARS-CoV-2 and vaccine development proceeded with unprecedented speed, HIV researchers at JHU recognized the importance of inclusion of PLWH in vaccine studies, as well as the potential implications of COVID-19 vaccinology to other vaccines, including HIV preventive and therapeutic vaccines. The immunosuppressive consequences of HIV on the effectiveness and durability of vaccine protection is not well characterized and is an important area of research. In addition to COVID vaccines, clinical research evaluating the durability and cellular immune responses to childhood and other adult vaccines is critical to determining if current vaccine schedules and recommendations are appropriate for PLWH. This SWG will focus on HIV and non-HIV vaccines and immunotherapeutics for PLWH to promote vaccine science education, foster research interest in vaccines and immunotherapeutics among early- and mid-level faculty, and coordinate with other SWGs to achieve these goals.